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Invasive species control: incorporating demographic data and seed dispersal into a management model for Rhododendron ponticum [PDF]
Rhododendron ponticum is a serious invasive alien plant in the British Isles and is of significant conservation and economic concern. Here, we integrate information on both the life-history and spatial dynamics of this species within an individual-based,
Edwards, Colin +9 more
core +1 more source
Documenting the presence and abundance of the neotropical mammals is the first step for understanding their population ecology, behavior and genetic dynamics in designing conservation plans.
Susana González +1 more
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
The Economic Impacts of Vertebrate Pests in Australia
Invasive animal pests have a wide variety of impacts on the economy, the environment and society. There is considerable information on these impacts for individual cases and regions, and McLeod (2004) attempted to value them nationwide for a whole range ...
Sinden, Jack A +5 more
core
Unusual Composition of the Sarezzano Reliquary Busts
The interdisciplinary study of two reliquary busts from Sarezzano (Piedmont, Italy) is a perfect example of the necessity to provide for material characterisation as a recurring common practice in historical studies and a mandatory step in conservation ...
Maria Labate +6 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Azurite, a natural mineral pigment consisting of basic copper carbonate (2CuCO3·Cu(OH)2), is one of the Middle Ages’ most common blue pigments. Why paintings originally coated with azurite appear blackened today remains debated.
Maria Labate +5 more
doaj +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Introduction Non-invasive assessment of coronary artery disease (CAD) in patients with hypertensive heart disease is still a major clinical challenge.
Sefer Bytyqi +4 more
core +1 more source

