Results 91 to 100 of about 12,620,879 (241)

Understandings of Down's syndrome and their place in the prenatal testing context [PDF]

, 2003
INTRODUCTION: There is a growing consensus that decisions about prenatal testing should a) be informed, and b) reflect the individual's attitudes and values.
Bryant, Louise Dorothy
core   +4 more sources

Clinical and medico-legal reflections on non-invasive prenatal testing

Open Medicine
Prenatal diagnosis has advanced dramatically, with both invasive and non-invasive techniques that enable a comprehensive evaluation of chromosomal and genetic disorders, thanks to considerable technological progress.
Gullo Giuseppe, Stabile Guglielmo, Ganduscio Silvia, Billone Valentina, Chitoran Elena, Sciorio Romualdo, Kowalcze Karolina, Krysiak Robert, Conti Eleonora, Zaami Simona, De Paola Lina   +10 more
doaj   +1 more source

Unlocking insights: Validating a comprehensive model for predicting spontaneous preterm delivery and microbial invasion in women facing preterm labor

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Preterm labor is a multifactorial syndrome with diverse etiologies such as infection, inflammation, uteroplacental dysfunction, stress, and immune dysregulation. Identifying women at high risk remains a challenge, and multivariate prediction models have been developed to enhance risk stratification.
Ester del Barco, Nerea Maiz, Clara Franco‐Jarava, Mireia Vargas, Silvia Arévalo, María A. Sánchez‐Durán, Carlota Rodó, Manel Mendoza, Marta Dalmau, Alba Casellas, Manuel Hernández‐González, Anna Suy, María Goya   +12 more
wiley   +1 more source

Clinical performance of non‐invasive prenatal testing (NIPT) using targeted cell‐free DNA analysis in maternal plasma with microarrays or next generation sequencing (NGS) is consistent across multiple controlled clinical studies

, 2015
To evaluate the clinical performance of non-invasive prenatal testing for trisomy 21, 18, and 13 using targeted cell-free DNA ...
Wang, Eric, Sparks, Andrew, Bo. Jacobsson, Musci, Thomas, Kypros Nicolaides, Karen White, Annette Batey, Jacobsson, Bo,, Madhumitha Balanarasimha, Renee Stokowski, Herb Brar, Desiree Hollemon, Nicolaides, Kypros, White, Karen, Thomas J. Musci, Stokowski, Renee, Batey, Annette, Andrew Sparks, Brar, Herb, Eric Wang, Hollemon, Desiree, Balanarasimha, Madhumitha   +21 more
core   +1 more source

The role of large language models as screening assistants in the diagnosis of placenta accreta spectrum pathologies

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Large language models (LLMs) are increasingly utilized in modern medicine. In obstetrics, their ability to interpret complex imaging, such as ultrasound images for placenta accreta spectrum (PAS), remains largely unexplored. This study aimed to investigate the capacity of multimodal LLMs to interpret sonographic images of placentae ...
Iason Psilopatis, Heidrun Schoenberger, Annkatrin Butenschoen, Thabea K. Musik, Georgia Levidou, Beatrice Mosimann, Gwendolin Manegold‐Brauer   +6 more
wiley   +1 more source

Technological Advances in Molecular Diagnostic Methods for Hereditary Diseases in Preconception and Prenatal Settings

Current Issues in Molecular Biology
Precision prevention and control of genetic diseases represent a major public health challenge. This paper provides a structured narrative review of advances in molecular diagnostic technologies across the preconception, preimplantation, and prenatal ...
Deyuan Kong, Jianing Zhao, Haichang Diao, Shuyao Qiu, Yuanyuan Peng, Tingting Liu   +5 more
doaj   +1 more source

Thermotherapy for prevention of perineal pain after vaginal birth: Evaluation of warm compresses and cold packs using a factorial randomized controlled trial

International Journal of Gynecology &Obstetrics, EarlyView.
RCT : randomized controlled trial, mean dif. (95% CI) : mean difference (95% confidence interval), sd : standard deviation. Abstract Objective Perineal pain is common after vaginal birth and might affect maternal well‐being and mother–infant bonding.
Pauline Blanc‐Petitjean, Clara Rollet, Géraldine Meunier, Laurent Mandelbrot, Camille Le Ray, Anne Alice Chantry   +5 more
wiley   +1 more source

Efficiency of Non-Invasive Prenatal Testing in Detecting Fetal Copy Number Variation: A Retrospective Cohort Study [PDF]

Li Yang,1 Jing Yang,2 Guosen Bu,3 Rui Han,1 Jiamila Rezhake,1 Xiaolin La1 1Center of Reproductive Medicine, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, People’s Republic of China; 2Department of Gynaecology, The Fifth ...
Yang J, Han R, Yang L, Bu G, La X, Rezhake J   +5 more
core  

Prenatal screening and diagnostic strategies for fetal genetic abnormalities: Comparison of international clinical guidelines

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract This study compares recommendations from international clinical guidelines regarding prenatal screening and diagnostic testing for fetal genetic abnormalities, including the role of non‐invasive prenatal testing (NIPT), invasive diagnostic procedures, and advanced genomic technologies.
Geovanna Saboia Veras, João Renato Bennini   +1 more
wiley   +1 more source

Longitudinal blood pressure trajectories before 20 weeks of gestation and adverse outcomes in women with chronic hypertension

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To explore the different patterns in early‐pregnancy mean arterial pressure (MAP) trajectories before 20 weeks of gestation in pregnant women with chronic hypertension, and whether it can stratify risk for adverse perinatal outcomes.
Haoyu Zuo, Yike Yang, Huanyu You, Chunjie Gong, Yan Wang   +4 more
wiley   +1 more source