Results 11 to 20 of about 12,620,879 (241)

Non-invasive prenatal testing for fetal chromosome abnormalities: review of clinical and ethical issues

The Application of Clinical Genetics, 2016
Jean Gekas,1,2 Sylvie Langlois,3 Vardit Ravitsky,4 François Audibert,5 David Gradus van den Berg,6 Hazar Haidar,4 François Rousseau2,7 1Prenatal Diagnosis Unit, Department of Medical Genetics and Pediatrics, Faculty of Medicine, Universit ...
Gekas J, Langlois S, Ravitsky V, Audibert F, van den Berg DG, Haidar H, Rousseau F   +6 more
doaj   +1 more source

Non-invasive prenatal testing: ethical issues explored [PDF]

European Journal of Human Genetics, 2009
This paper explores the ethical implications of introducing non-invasive prenatal diagnostic tests (NIPD tests) in prenatal screening for foetal abnormalities. NIPD tests are easy and safe and can be performed early in pregnancy. Precisely because of these features, it is feared that informed consent may become more difficult, that both testing and ...
de Jong, Antina, Dondorp, Wybo J., de Die-Smulders, Christine E. M., Frints, Suzanne G. M., de Wert, Guido M. W. R.   +4 more
openaire   +5 more sources

Non-invasive prenatal testing: a review of international implementation and challenges

International Journal of Women's Health, 2015
Megan Allyse,1 Mollie A Minear,2 Elisa Berson,3 Shilpa Sridhar,3 Margaret Rote,3 Anthony Hung,3 Subhashini Chandrasekharan4 1Institute for Health and Aging, University of California San Francisco, San Francisco, California, USA, 2Duke Science & ...
Allyse M, Minear MA, Berson E, Sridhar S, Rote M, Hung A, Chandrasekharan S   +6 more
doaj   +1 more source

Non-Invasive Prenatal Testing in the Kingdom of Saudi Arabia: Current Status of Adoption and Roadmap for the Future [PDF]

The Application of Clinical Genetics
Majid Alfadhel,1– 3 Amal AlHashem,4,5 Wesam Kurdi,6 Maha Tulbah,6 Saleh AlGamdi5,7 ,† Mohammed Almannai,1,2 Iman AlAmoudi,8 Mariam M AlEissa,5,9 Nada AlAgil,10 Soha Tashkandi,11 Nancy Awad,12 Rita Ojeil13 1Medical Genomics Research Department, King ...
Alfadhel M, AlHashem A, Kurdi W, Tulbah M, AlGamdi S, Almannai M, AlAmoudi I, AlEissa MM, AlAgil N, Tashkandi S, Awad N, Ojeil R   +11 more
doaj   +1 more source

Routinization of prenatal screening with the non-invasive prenatal test: pregnant women’s perspectives [PDF]

European Journal of Human Genetics, 2021
AbstractDue to the favorable test characteristics of the non-invasive prenatal test (NIPT) in the screening of fetal aneuploidy, there has been a strong and growing demand for implementation. In the Netherlands, NIPT is offered within a governmentally supported screening program as a first-tier screening test for all pregnant women (TRIDENT-2 study ...
Karuna R. M. van der Meij, Annabel Njio, Linda Martin, Janneke T. Gitsels-van der Wal, Mireille N. Bekker, Elsbeth H. van Vliet-Lachotzki, A. Jeanine E. M. van der Ven, Adriana Kater-Kuipers, Danielle R. M. Timmermans, Erik A. Sistermans, Robert-Jan H. Galjaard, Lidewij Henneman   +11 more
openaire   +3 more sources

Relevance of Invasive Testing in Era of Non-Invasive Testing for Prenatal Chromosomal Abnormalities

Gynecology Obstetrics & Reproductive Medicine, 2022
Prenatal screening for chromosomal abnormalities has two components i.e. prenatal screening (maternal serum screening and cell-free fetal DNA screening) and prenatal diagnosis (chorionic villus sampling, amniocentesis, and cordocentesis).
Abhijeet Kumar, Madhusudan Dey, Devendra Arora   +2 more
doaj   +1 more source

Non-invasive prenatal testing for aneuploidy screening [PDF]

BMJ, 2020
### What you need to know A 36 year old woman attends her general practice at 8 weeks in her second pregnancy. She has heard there is a new blood test she can have which will test for chromosomal anomalies and wants to find out more. In many countries, screening for trisomies 21 (Down’s syndrome), 18 (Edward’s syndrome), and 13 (Patau’s syndrome) is
Spencer, R, Hewitt, H, McCarthy, L, Wimalasundera, R, Pandya, P   +4 more
openaire   +3 more sources

Reappraisal of evolving methods in non-invasive prenatal screening: Discovery, biology and clinical utility

Heliyon, 2023
Non-invasive prenatal screening (NIPS) offers an opportunity to screen or determine features associated with the fetus. Earlier, prenatal testing was done with cytogenetic procedures like karyotyping or fluorescence in-situ hybridization, which ...
Riyaz Ahmad Rather, Subhas Chandra Saha
doaj   +1 more source

Trends in Non-invasive Prenatal Screening and Invasive Testing in Denmark (2000–2019) and Israel (2011–2019)

Frontiers in Medicine, 2021
Introduction: Following the wide distribution of non-invasive prenatal genetic screening (NIPS), numerous studies have reported a decline in total invasive tests in the recent years, up to 50–70% in some countries.
Lena Sagi-Dain, Amihood Singer, Olav B. Petersen, Olav B. Petersen, Stina Lou, Ida Vogel, Ida Vogel   +6 more
doaj   +1 more source

The Effect of Freezing on Non-invasive Prenatal Testing [PDF]

Scientific Reports, 2019
AbstractPlasma cryopreservation is unavoidable in China, due to technical specifications requiring storage of additional plasma at −80 degrees for three years. However, the effect of freezing on non-invasive prenatal testing (NIPT) is still uncertain. We collected 144 euploid pregnant samples, 22 on trisomy 21, 4 on trisomy 13, and 3 on trisomy 18, by ...
Xie, Xiaolei, Li, Fuguang, Tan, Weihe, Yin, Weiguo, Chen, Feiyan, Guo, Xiaoyan   +5 more
openaire   +2 more sources