Results 11 to 20 of about 15,755 (254)

Calculation of Fetal Fraction for Non-Invasive Prenatal Testing [PDF]

BioTech, 2021
Estimating the fetal fraction of DNA in a pregnant mother’s blood is a risk-free, non-invasive way of predicting fetal aneuploidy. It is a rapidly developing field of study, offering researchers a plethora of different complementary methods. Such methods
Matthew Cserhati
doaj   +3 more sources

A new era in prenatal care: non-invasive prenatal testing in Switzerland

Swiss Medical Weekly, 2014
QUESTIONS UNDER STUDY: Prenatal care has been significantly influenced by the introduction of non-invasive prenatal testing (NIPT) for aneuploidies in 2012. The aim of this study was to describe the current impact of NIPT on prenatal care.
Gwendolin Manegold-Brauer, Anjeung Kang Bellin, Sinuhe Hahn, Christian De Geyter, Johanna Buechel, Irene Hoesli, Olav Lapaire   +6 more
doaj   +5 more sources

Update in non-invasive prenatal testing [PDF]

Minerva Ginecologica, 2019
Non-invasive prenatal testing (NIPT) has revolutionized the approach to prenatal diagnosis and, to date, it is the most superior screening method for the common autosomal aneuploidies, mostly trisomy 21. This screening is having a significant population-wide impact on the uptake of conventional screening and diagnostic testing.
D'ambrosio, V, Squarcella, A, Vena, F, Di Mascio, D, Corno, S, Pajno, C, Piccioni, MG, Brunelli, R, Pizzuti, A, Benedetti Panici, P, Giancotti, A.   +10 more
openaire   +2 more sources

Relevance of Invasive Testing in Era of Non-Invasive Testing for Prenatal Chromosomal Abnormalities

Gynecology Obstetrics & Reproductive Medicine, 2022
Prenatal screening for chromosomal abnormalities has two components i.e. prenatal screening (maternal serum screening and cell-free fetal DNA screening) and prenatal diagnosis (chorionic villus sampling, amniocentesis, and cordocentesis).
Abhijeet Kumar, Madhusudan Dey, Devendra Arora   +2 more
doaj   +1 more source

Reappraisal of evolving methods in non-invasive prenatal screening: Discovery, biology and clinical utility

Heliyon, 2023
Non-invasive prenatal screening (NIPS) offers an opportunity to screen or determine features associated with the fetus. Earlier, prenatal testing was done with cytogenetic procedures like karyotyping or fluorescence in-situ hybridization, which ...
Riyaz Ahmad Rather, Subhas Chandra Saha
doaj   +1 more source

Non-invasive prenatal testing for aneuploidy screening [PDF]

BMJ, 2020
### What you need to know A 36 year old woman attends her general practice at 8 weeks in her second pregnancy. She has heard there is a new blood test she can have which will test for chromosomal anomalies and wants to find out more. In many countries, screening for trisomies 21 (Down’s syndrome), 18 (Edward’s syndrome), and 13 (Patau’s syndrome) is
Spencer, R, Hewitt, H, McCarthy, L, Wimalasundera, R, Pandya, P   +4 more
openaire   +3 more sources

Routinization of prenatal screening with the non-invasive prenatal test: pregnant women’s perspectives [PDF]

European Journal of Human Genetics, 2021
AbstractDue to the favorable test characteristics of the non-invasive prenatal test (NIPT) in the screening of fetal aneuploidy, there has been a strong and growing demand for implementation. In the Netherlands, NIPT is offered within a governmentally supported screening program as a first-tier screening test for all pregnant women (TRIDENT-2 study ...
Karuna R. M. van der Meij, Annabel Njio, Linda Martin, Janneke T. Gitsels-van der Wal, Mireille N. Bekker, Elsbeth H. van Vliet-Lachotzki, A. Jeanine E. M. van der Ven, Adriana Kater-Kuipers, Danielle R. M. Timmermans, Erik A. Sistermans, Robert-Jan H. Galjaard, Lidewij Henneman   +11 more
openaire   +3 more sources

Trends in Non-invasive Prenatal Screening and Invasive Testing in Denmark (2000–2019) and Israel (2011–2019)

Frontiers in Medicine, 2021
Introduction: Following the wide distribution of non-invasive prenatal genetic screening (NIPS), numerous studies have reported a decline in total invasive tests in the recent years, up to 50–70% in some countries.
Lena Sagi-Dain, Amihood Singer, Olav B. Petersen, Olav B. Petersen, Stina Lou, Ida Vogel, Ida Vogel   +6 more
doaj   +1 more source

The Effect of Freezing on Non-invasive Prenatal Testing [PDF]

Scientific Reports, 2019
AbstractPlasma cryopreservation is unavoidable in China, due to technical specifications requiring storage of additional plasma at −80 degrees for three years. However, the effect of freezing on non-invasive prenatal testing (NIPT) is still uncertain. We collected 144 euploid pregnant samples, 22 on trisomy 21, 4 on trisomy 13, and 3 on trisomy 18, by ...
Xie, Xiaolei, Li, Fuguang, Tan, Weihe, Yin, Weiguo, Chen, Feiyan, Guo, Xiaoyan   +5 more
openaire   +2 more sources

Testing Times: The Social Life of Non-invasive Prenatal Testing [PDF]

Science, Technology and Society, 2020
Non-invasive prenatal testing (NIPT) is a genomic technology used to predict the chance of a foetus having a genetic condition. Despite the immediacy of this technology’s integration into clinical practice, there is a dearth of evidence outlining how both patients and professionals experience NIPT on the ground.
Thomas, Gareth M., Rothman, Barbara Katz, Strange, Heather, Latimer, Joanna   +3 more
openaire   +1 more source