Results 201 to 210 of about 12,620,879 (241)

Insurance and geographic variations in non‐invasive prenatal testing

Prenatal Diagnosis, 2022
Key pointsWhat is already known about this topic? Single‐site studies suggest racial, ethnic, and insurance disparities in use of Non‐invasive prenatal testing (NIPT). Population‐level research from outside the U.S. highlights significant geographic variations in NIPT uptake. What does this study add?
Jacqueline Ellison, Catharine Wang, Christina Yarrington, Philip Connors, Amresh Hanchate   +4 more
openaire   +2 more sources

Non-invasive prenatal testing for Down syndrome

Seminars in Fetal and Neonatal Medicine, 2014
Prenatal screening and diagnosis of Down syndrome and other major aneuploidies may be transformed following the identification of cell-free fetal DNA in maternal plasma at the end of the last millennium. Next generation sequencing has enabled the development of tests that accurately predict the presence of fetal trisomies by analysis of cell-free DNA ...
Philip, Twiss, Melissa, Hill, Rebecca, Daley, Lyn S, Chitty   +3 more
openaire   +2 more sources

Realising the promise of non-invasive prenatal testing

BMJ, 2015
It should transform the quality of antenatal care The presence in maternal plasma of cell-free fetal DNA, which is pregnancy specific1 and represents the whole of the fetal genome,2 offers enormous promise for the development of a wide range of prenatal genetic tests.
Lyn S, Chitty, Mark, Kroese
openaire   +2 more sources

Non-invasive Prenatal Testing (NIPT)

DeckerMed Obstetrics and Gynecology, 2019
Non-invasive prenatal testing (NIPT) is a screening test that can determine if a pregnancy is at high risk for the common aneuploidies by analyzing cell-free fetal DNA in the maternal bloodstream. The screening includes trisomy 21, trisomy 18, and trisomy 13, with the option of screening for sex chromosome aneuploidy and fetal sex.
Mary-Alice Abbott, Courtney Manning
openaire   +1 more source

Non-invasive prenatal testing in the context of IVF and PGT-A

Best Practice & Research Clinical Obstetrics & Gynaecology, 2021
The high incidence of chromosome aneuploidy in human gametes and embryos is a major cause of in vitro fertilization (IVF) failure and miscarriage. In order to improve live birth rates with single embryo transfer, the use of preimplantation genetic testing for aneuploidy (PGT-A) has significantly increased.
Dana Kimelman, Mary Ellen Pavone
openaire   +2 more sources

How ‘non-invasive’ is non-invasive prenatal testing?

Journal of Medical Ethics
The invasiveness of a medical intervention is considered to be morally important and can have a significant influence on acceptability and uptake. De Marco et al propose a novel account of the invasiveness of medical interventions that better reflects the common understanding of the term ...
openaire   +2 more sources

Non-invasive prenatal testing of pregnancies at risk for phenylketonuria

Archives of Disease in Childhood - Fetal and Neonatal Edition, 2018
Background Phenylketonuria (PKU) is a common metabolic disorder caused predominately by mutations in the phenylalanine hydroxylase (PAH) gene. The aim of the study was to design and validate the performance of a non-invasive prenatal test (NIPT) for PKU using circulating single molecule amplification and ...
Huikun Duan, Ning Liu, Zhenhua Zhao, Yiqian Liu, Yin Wang, Zhifeng Li, Mengnan Xu, David S Cram, Xiangdong Kong   +8 more
openaire   +2 more sources

Non-invasive prenatal testing.

Australian family physician, 2018
Non-invasive prenatal testing (NIPT), also known as cell-free DNA testing and non-invasive prenatal screening (NIPS), is an important addition to the range of screening tests for fetal chromosomal abnormalities. For trisomy 21 in particular, NIPT is superior to other screening modalities.
openaire   +1 more source

Non-Invasive Prenatal Testing: Ethics and Policy Considerations

Journal of Obstetrics and Gynaecology Canada, 2014
New technologies analyzing fetal DNA in maternal blood have led to the wide commercial availability of non-invasive prenatal testing (NIPT). We present here for clinicians the ethical and policy issues related to an emerging practice option. Although NIPT presents opportunities for pregnant women, particularly women who are at increased risk of having ...
Meredith, Vanstone, Carol, King, Barbra, de Vrijer, Jeff, Nisker   +3 more
openaire   +2 more sources

[Non-invasive prenatal testing is a breakthrough in prenatal screening].

Ugeskrift for laeger, 2017
Non-invasive prenatal testing (NIPT) using cell-free fetal DNA from the peripheral blood of the pregnant woman has become a possibility within recent years, but is not yet implemented in Denmark. NIPT has proven to be very efficient in the screening for especially trisomi 21.
Louise Stig, Hornstrup, Louise, Ambye, Steen, Sørensen, Finn Stener, Jørgensen   +3 more
openaire   +1 more source