Results 31 to 40 of about 4,684 (217)

Discordant performances of non-invasive prenatal testing for foetal trisomy 21 screening in subgroups of pregnancies

Journal of Obstetrics and Gynaecology, 2023
Background Non-invasive prenatal testing (NIPT) has been widely adopted as an approach for foetal aneuploidy screening. This study was to evaluate the performance of NIPT for foetal T21 detection in subgroups of pregnancies and the correlation between Z ...
Feng Suo, Yi Wang, Na Wang, Yawen Wang, Mingming Liao, Jingjing Wang, Chuanxia Wang, Yan Zhang, Man Zhang, Chu Zhang, Maosheng Gu, Lingshan Gou   +11 more
doaj   +1 more source

Sünnieelne mitteinvasiivne geneetiline sõeluuring – võidukäik ja puudujäägid [PDF]

, 2016
Paljudes Euroopa maades on sünnieelne kromosoomhaiguste sõeluuring riiklikult korraldatud: rasedatele pakutakse vereseerumi markerite määramist ning loote ultraheliuuringuid.
Krjutškov, Kaarel, Reimand, Tiia, Roost, Anne Mari   +2 more
core   +2 more sources

Whole genome non-invasive prenatal testing in prenatal screening algorithm: clinical experience from 12,700 pregnancies

BMC Pregnancy and Childbirth, 2022
Background A fast adoption of a non–invasive prenatal testing (NIPT) in clinical practice is a global tendency last years. Firstly, in Russia according a new regulation it was possible to perform a widescale testing of pregnant women in chromosomal ...
Elena E. Baranova, Olesya V. Sagaydak, Alexandra M. Galaktionova, Ekaterina S. Kuznetsova, Madina T. Kaplanova, Maria V. Makarova, Maxim S. Belenikin, Anton S. Olenev, Ekaterina N. Songolova   +8 more
doaj   +1 more source

Enlarged NT (≥3.5 mm) in the first trimester - Not all chromosome aberrations can be detected by NIPT [PDF]

, 2016
__Background:__ Since non-invasive prenatal testing (NIPT) in maternal blood became available, we evaluated which chromosome aberrations found in our cohort of fetuses with an enlarged NT in the first trimester of pregnancy (tested with SNP microarray ...
Bos, M.J. (Marnix), Diderich, K.E.M. (Karin), Galjaard, R-J.H. (Robert-Jan), Go, A.T.J.I. (Attie), Govaerts, L.C. (Lutgarde), Joosten, A-M.S (Marieke), Knapen, M.F.C.M. (Maarten), Koningen, M. (Mieke), Looye-Bruinsma, G.A.G. (Gerda), Srebniak, M.I. (Malgorzata), Van Opstal, A.R.M. (Diane), Wit, M.C. (Merel) de   +11 more
core   +1 more source

Non-invasive prenatal testing (NIPT): a better option for patients [PDF]

Molecular Cytogenetics, 2014
At present there are two methods to determine the chromosome health of unborn fetus in pregnant women. One is through maternal serum screening that is considered as simple but less sensitive method and the second options involves invasive methods like amniocentesis or chorionic villus sampling (CVS) for women who are found to be positive in maternal ...
openaire   +2 more sources

Investigational Management for a Positive NIPT Result - Case Report [PDF]

Modern Medicine
Non-invasive prenatal testing (NIPT), since its introduction in 2011, has revolutionized prenatal screening, becoming widely used globally and replacing traditional screening methods in developed countries.
Elena Evelina STOICA, Laurentiu Camil BOHILTEA, Delia-Maria Gradinaru-FOMETESCU, Monica Mihaela CIRSTOIU   +3 more
doaj   +1 more source

Causes of aberrant non-invasive prenatal testing for aneuploidy: A systematic review

Taiwanese Journal of Obstetrics & Gynecology, 2020
Non-invasive prenatal testing (NIPT) is performed worldwide to detect common chromosomal aneuploidies. The analysis of cell-free DNA (cfDNA) in maternal blood for NIPT is highly accurate for the detection of the main fetal trisomies: 21,18, and 13 ...
Osamu Samura, Aikou Okamoto
doaj   +1 more source

Abnormal plasma DNA profiles in early ovarian cancer using a non-invasive prenatal testing platform: Implications for cancer screening [PDF]

, 2016
Background: Non-invasive prenatal testing (NIPT) identifies fetal aneuploidy by sequencing cell-free DNA in the maternal plasma. Pre-symptomatic maternal malignancies have been incidentally detected during NIPT based on abnormal genomic profiles.
Cohen, P, Flowers, N, Hannan, N, Hui, L, Pertile, M, Tong, S   +5 more
core   +2 more sources

Non-invasive prenatal testing: a revolutionary journey in prenatal testing

Frontiers in Medicine, 2023
Non-invasive prenatal testing (NIPT) is a pioneering technique that has consistently advanced the field of prenatal testing to detect genetic abnormalities and conditions with the aim of decreasing the incidence and prevalence of inherited conditions ...
Malak Abedalthagafi, Malak Abedalthagafi, Shahad Bawazeer, Romy I. Fawaz, A. Merrihew Heritage, Nouf M. Alajaji, Eissa Faqeih   +6 more
doaj   +1 more source

Innovative method for reducing uninformative calls in non-invasive prenatal testing [PDF]

, 2018
Non-invasive prenatal testing or NIPT is currently among the top researched topic in obstetric care. While the performance of the current state-of-the-art NIPT solutions achieve high sensitivity and specificity, they still struggle with a considerable ...
Budis, Jaroslav, Duris, Frantisek, Gazdarica, Juraj, Gazdaricova, Iveta, Harsanyova, Maria, Kucharik, Marcel, Minarik, Gabriel, Nagy, Balint, Radvanszky, Jan, Sekelska, Martina, Strieskova, Lucia, Szemes, Tomas, Szucs, Gabor, Turna, Jan   +13 more
core   +2 more sources