Results 1 to 10 of about 6,441 (177)

Intermediate-dose cytarabine is an effective therapy for adults with non-Langerhans cell histiocytosis [PDF]

Orphanet Journal of Rare Diseases, 2022
Background Non-Langerhans cell histiocytosis, including Erdheim–Chester disease (ECD), Rosai–Dorfman disease (RDD), indeterminate cell histiocytosis (ICH), and unclassified histiocytosis, is a rare disorder lacking a standard treatment strategy.
Ting Liu, Hua-cong Cai, Hao Cai, Miao Chen, Wei Zhang, Jian Li, Dao-bin Zhou, Xin-xin Cao   +7 more
doaj   +6 more sources

Successful Treatment of Non-Langerhans Cell Histiocytosis With Topical Rapamycin in Two Pediatric Cases [PDF]

Clinical, Cosmetic and Investigational Dermatology, 2022
Raden Mohamad Rendy Ariezal Effendi, Trustia Rizqandaru, Renata Yuliasari, Srie Prihianti Gondokaryono, Inne Arline Diana, Reiva Farah Dwiyana Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr.
Effendi RMRA, Rizqandaru T, Yuliasari R, Gondokaryono SP, Diana IA, Dwiyana RF   +5 more
doaj   +4 more sources

A Rare Case of Erdheim-Chester Disease (Non-Langerhans Cell Histiocytosis) with Concurrent Langerhans Cell Histiocytosis: A Diagnostic and Therapeutic Challenge [PDF]

Case Reports in Hematology, 2018
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocyte disorder most commonly characterized by multifocal osteosclerotic lesions of the long bones demonstrating sheets of foamy histiocyte infiltrates on biopsy with or without histiocytic ...
Hamza Hashmi, Drew Murray, John Greenwell, Marwan Shaikh, Soumit Basu, Maxwell Krem   +5 more
doaj   +5 more sources

Intra-arterial Melphalan for Neurologic Non-Langerhans Cell Histiocytosis. [PDF]

Neurology, 2021
Histiocytic neoplasms are rare hematologic disorders characterized by pathologic infiltration of activated histiocytes in affected tissues. The treatment of histiocytic neoplasms, including Langerhans cell histiocytosis (LCH) and non-LCH, has advanced in recent years owing to targeted kinase inhibitors (BRAF and MEK) as patients with somatic mutations ...
Francis JH, Gobin YP, Alshiekh Nasany R, Knopman J, Ulaner GA, Panageas KS, Hatzoglou V, Salvaggio K, Abramson DH, Patsalides A, Diamond EL.   +10 more
europepmc   +4 more sources

Case of Non-Langerhans Cell Histiocytosis in a Person Living with HIV - Clinical and Therapeutic Challenge [PDF]

Journal of the International Association of Providers of AIDS Care, 2022
Non-Langerhans cell histiocytosis is a rare disease which seldom affects adults. We report a case of a 32-year-old Bulgarian woman living with HIV. She developed severe anemia, extreme splenomegaly, requiring splenectomy and vertebral tumor formations ...
Nina Yancheva, Dimitar Strashimirov, Dragomir Dardanov, Bojidar Kamenov, Atanas Radinoff   +4 more
doaj   +2 more sources

High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis. [PDF]

Blood, 2017
Key Points Some 10.1% of adults with non–Langerhans cell histiocytosis have a concomitant myeloid neoplasm with each often harboring distinct mutations. The presence of distinct kinase mutations in histiocytosis and myeloid neoplasms resulted in discordant responses to targeted therapy.
Papo M, Diamond EL, Cohen-Aubart F, Emile JF, Roos-Weil D, Gupta N, Durham BH, Ozkaya N, Dogan A, Ulaner GA, Rampal R, Kahn JE, Sené T, Charlotte F, Hervier B, Besnard C, Bernard OA, Settegrana C, Droin N, Hélias-Rodzewicz Z, Amoura Z, Abdel-Wahab O, Haroche J.   +22 more
europepmc   +4 more sources

Renovascular Hypertension: Unraveling a Case of Mixed Histiocytosis

Annals of Internal Medicine: Clinical Cases, 2023
Renovascular hypertension is a cause of secondary hypertension. Atherosclerotic renal artery stenosis and fibromuscular dysplasia are the main causes, but other rare entities can involve the renal arteries.
Pedro Marques, Joana Tender Vieira, Inês M. de Sá, André Carvalho, João Rocha-Neves, Irene Gullo, Edite Pereira, José Manuel Lopes, Jorge Almeida   +8 more
doaj   +1 more source

Adult-onset of Langerhans cell histiocytosis: a clinical case

Alʹmanah Kliničeskoj Mediciny, 2021
Langerhans cell histiocytosis is mainly diagnosed in children, and its manifestation in adult age is quite uncommon. Skin rashes may be non-specific and mimic a number of dermatoses.
Olga V. Chernysheva, Olga V. Dorokhina, Albina N. Khlebnikova, Elena V. Selezneva   +3 more
doaj   +1 more source

Adult Langerhans cell histiocytosis with a rare BRAF V600E and V600D mutation, diagnosed through oral manifestations

Advances in Oral and Maxillofacial Surgery, 2022
Langerhans cell histiocytosis, is a rare disorder characterized by an aberrant proliferation of Langerhans-type cells that infiltrates and replaces the involved tissues.
Soukaïna Oujdad, Saadia Zafad, Hicham El Attar, Ihsane Ben Yahya   +3 more
doaj   +1 more source

Cutaneous Rosai-Dorfman Disease - A Rare Non-Langerhans Cell Histiocytosis

JK Science
Cutaneous Rosai-Dorfman disease is classified as non-Langerhans cell histiocytosis. It is a benign lymphoproliferative disorder involving only skin and subcutaneous tissue, which is rare and not well documented.
Afthab Jameela Wahab, S. Athilakshmi, Nivvedhetha S   +2 more
doaj   +1 more source