Results 1 to 10 of about 460 (122)

Intermediate-dose cytarabine is an effective therapy for adults with non-Langerhans cell histiocytosis [PDF]

Orphanet Journal of Rare Diseases, 2022
Background Non-Langerhans cell histiocytosis, including Erdheim–Chester disease (ECD), Rosai–Dorfman disease (RDD), indeterminate cell histiocytosis (ICH), and unclassified histiocytosis, is a rare disorder lacking a standard treatment strategy.
Ting Liu, Hua-cong Cai, Hao Cai, Miao Chen, Wei Zhang, Jian Li, Dao-bin Zhou, Xin-xin Cao   +7 more
doaj   +7 more sources

Case of Non-Langerhans Cell Histiocytosis in a Person Living with HIV - Clinical and Therapeutic Challenge [PDF]

Journal of the International Association of Providers of AIDS Care, 2022
Non-Langerhans cell histiocytosis is a rare disease which seldom affects adults. We report a case of a 32-year-old Bulgarian woman living with HIV. She developed severe anemia, extreme splenomegaly, requiring splenectomy and vertebral tumor formations ...
Nina Yancheva, Dimitar Strashimirov, Dragomir Dardanov, Bojidar Kamenov, Atanas Radinoff   +4 more
doaj   +4 more sources

Successful Treatment of Non-Langerhans Cell Histiocytosis With Topical Rapamycin in Two Pediatric Cases

Clinical, Cosmetic and Investigational Dermatology, 2022
Raden Mohamad Rendy Ariezal Effendi, Trustia Rizqandaru, Renata Yuliasari, Srie Prihianti Gondokaryono, Inne Arline Diana, Reiva Farah Dwiyana Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr.
Effendi RMRA, Rizqandaru T, Yuliasari R, Gondokaryono SP, Diana IA, Dwiyana RF   +5 more
doaj   +5 more sources

A Rare Case of Erdheim-Chester Disease (Non-Langerhans Cell Histiocytosis) with Concurrent Langerhans Cell Histiocytosis: A Diagnostic and Therapeutic Challenge [PDF]

Case Reports in Hematology, 2018
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocyte disorder most commonly characterized by multifocal osteosclerotic lesions of the long bones demonstrating sheets of foamy histiocyte infiltrates on biopsy with or without histiocytic ...
Hamza Hashmi, Drew Murray, John Greenwell, Marwan Shaikh, Soumit Basu, Maxwell Krem   +5 more
doaj   +5 more sources

Intra-arterial Melphalan for Neurologic Non-Langerhans Cell Histiocytosis [PDF]

Neurology, 2021
Histiocytic neoplasms are rare hematologic disorders characterized by pathologic infiltration of activated histiocytes in affected tissues. The treatment of histiocytic neoplasms, including Langerhans cell histiocytosis (LCH) and non-LCH, has advanced in recent years owing to targeted kinase inhibitors (BRAF and MEK) as patients with somatic mutations ...
Jasmine H. Francis, Y. Pierre Gobin, Ruham Alshiekh Nasany, Jared Knopman, Gary A. Ulaner, Katherine S. Panageas, Vaios Hatzoglou, Kim Salvaggio, David H. Abramson, Athos Patsalides, Eli L. Diamond   +10 more
openaire   +4 more sources

An unusual case of intracerebral Non-Langerhans cell histiocytosis with review of the literature [PDF]

Diagnostic Pathology, 2007
Conclusion This case shows the unusual manifestation of a primary intracerebral Non-Langerhans cell histiocytosis, which begins as a solid mass around the sellar region and shows a remarkable extension as a flat lining of inner and outer liquor spaces.
Mueller, K., Trippel, M., Berlis, Ansgar, Janzarik, W., Volk, B.   +4 more
openaire   +5 more sources

Non-Langerhans cell histiocytosis in a child with Kawasaki disease

BMJ Case Reports, 2009
Polymorphous skin rashes are one of the major presentations in children with Kawasaki disease. This report describes an unusual presentation of a skin rash (non-Langerhans cell histiocytosis) in a 4-month-old baby with resistance to intravenous immunoglobulin (IVIG) treatment and coronary artery dilatation.
Hong-Ren Yu, Kuender D. Yang, Chih-Chiang Wu, Tsung-Hsien Yang, Chi-Di Liang, Ho-Chang Kuo, Yi-Ju Chen   +6 more
openaire   +6 more sources

A rare cutaneous lesion in the neonatal period: The non-Langerhans cell histiocytosis

Marmara Medical Journal, 2020
The non-Langerhans cell histiocytosis (non-LCH) is a group of diseases characterized by cutaneous involvement in the neonatal period. The non-LCH affects less than 1 in 200,000 children born each year. A definitive diagnosis is important for the treatment of the disease.
Adnan BARUTCU, Ferda OZLU, Hacer YAPICIOGLU YILDIZDAS, Mehmet SATAR   +3 more
openaire   +5 more sources

PAPULAR HISTIOCYTOSIS OF HEAD : TYPE OF NON - LANGERHANS CELLS HISTIOCYTOSIS [PDF]

Journal of Evolution of Medical and Dental Sciences, 2014
Papular histiocytosis of the head also known as benign cephalic histiocytosis is a rare, self-limiting histiocytosis that typically starts in early childhood. 1 Erythematous macules, papules and nodules develop on cheeks and spread to the forehead, earlobes and neck. Lesions are asymptomatic, gradually become reddish brown and may spread to involve the
Gaurav Murti, Anil K. Gupta
openaire   +2 more sources

MEK Inhibition with Trametinib in Patients with Non-Langerhans Cell Histiocytosis

Blood, 2019
Background: Activation of the MAPK pathway through BRAF mutations or other molecular alterations is a hallmark of the non-Lagerhans cell histiocytosis (non-LCH) such Erdheim-Chester disease (ECD) or Rosai-Dorfman disease (RDD). Conventional clinical molecular testing of tumor tissue fails to identify targetable molecular alteration in about one third ...
Aaron M. Goodman, Vaijayanthi Kandadai Raghavan, Tamara G. Barnes, Filip Janku, Harsh Patel, Razelle Kurzrock   +5 more
openaire   +3 more sources