Results 1 to 10 of about 9,332 (243)

Case of Non-Langerhans Cell Histiocytosis in a Person Living with HIV - Clinical and Therapeutic Challenge. [PDF]

J Int Assoc Provid AIDS Care, 2022
Non-Langerhans cell histiocytosis is a rare disease which seldom affects adults. We report a case of a 32-year-old Bulgarian woman living with HIV. She developed severe anemia, extreme splenomegaly, requiring splenectomy and vertebral tumor formations leading to fracture.
Yancheva N, Strashimirov D, Dardanov D, Kamenov B, Radinoff A.   +4 more
europepmc   +6 more sources

Successful Treatment of Non-Langerhans Cell Histiocytosis With Topical Rapamycin in Two Pediatric Cases. [PDF]

Clin Cosmet Investig Dermatol, 2022
Non-Langerhans cell histiocytosis (non-LCH) is a group of diseases characterized by the proliferation of histiocytes in tissues that is excluded from the diagnostic criteria for LCH. Juvenile xanthogranuloma (JXG) and benign cephalic histiocytosis (BCH) are the most common types of cutaneous non-LCH.
Effendi RMRA, Rizqandaru T, Yuliasari R, Gondokaryono SP, Diana IA, Dwiyana RF.   +5 more
europepmc   +7 more sources

A Rare Case of Erdheim-Chester Disease (Non-Langerhans Cell Histiocytosis) with Concurrent Langerhans Cell Histiocytosis: A Diagnostic and Therapeutic Challenge. [PDF]

Case Rep Hematol, 2018
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocyte disorder most commonly characterized by multifocal osteosclerotic lesions of the long bones demonstrating sheets of foamy histiocyte infiltrates on biopsy with or without histiocytic infiltration of extraskeletal tissues.
Hashmi H, Murray D, Greenwell J, Shaikh M, Basu S, Krem M.   +5 more
europepmc   +7 more sources

Intra-arterial Melphalan for Neurologic Non-Langerhans Cell Histiocytosis. [PDF]

Neurology, 2021
Histiocytic neoplasms are rare hematologic disorders characterized by pathologic infiltration of activated histiocytes in affected tissues. The treatment of histiocytic neoplasms, including Langerhans cell histiocytosis (LCH) and non-LCH, has advanced in recent years owing to targeted kinase inhibitors (BRAF and MEK) as patients with somatic mutations ...
Francis JH, Gobin YP, Alshiekh Nasany R, Knopman J, Ulaner GA, Panageas KS, Hatzoglou V, Salvaggio K, Abramson DH, Patsalides A, Diamond EL.   +10 more
europepmc   +6 more sources

High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis. [PDF]

Blood, 2017
Key Points Some 10.1% of adults with non–Langerhans cell histiocytosis have a concomitant myeloid neoplasm with each often harboring distinct mutations. The presence of distinct kinase mutations in histiocytosis and myeloid neoplasms resulted in discordant responses to targeted therapy.
Papo M, Diamond EL, Cohen-Aubart F, Emile JF, Roos-Weil D, Gupta N, Durham BH, Ozkaya N, Dogan A, Ulaner GA, Rampal R, Kahn JE, Sené T, Charlotte F, Hervier B, Besnard C, Bernard OA, Settegrana C, Droin N, Hélias-Rodzewicz Z, Amoura Z, Abdel-Wahab O, Haroche J.   +22 more
europepmc   +6 more sources

Case report: Pulmonary non-Langerhans cell histiocytosis in a dog with acute interstitial granulomatous pneumonia. [PDF]

Front Vet Sci
BackgroundPulmonary involvement of Non-Langerhans Cell Histiocytosis (PNLCH) is a rare cause of interstitial pulmonary disease in people and are classified as either Erdheim-Chester disease (ECD) or Rosai-Dorfman disease (RDD). In veterinary medicine, feline pulmonary Langerhans cell histiocytosis (PLCH) has been identified as an infiltrative ...
Granger KL, Williams K, Ohlendorf A, Shropshire S, Hall KE.   +4 more
europepmc   +5 more sources

Novel actionable ROS1::GIT2 fusion in non-Langerhans cell histiocytosis with central nervous system involvement. [PDF]

Acta Neuropathol, 2023
Bedics G, Csóka M, Reiniger L, Varga E, Liptai Z, Papp G, Bekő A, Cervi C, Bödör C, Scheich B.   +9 more
europepmc   +5 more sources

Disseminated non-Langerhans cell histiocytosis with an IRF2BP2-NTRK1 gene fusion identified by next-generation sequencing. [PDF]

JAAD Case Rep, 2020
Chan WH, Shah A, Bae G, Hambro C, Martin BA, Brown R, Novoa R, Kwong BY.   +7 more
europepmc   +7 more sources

An unusual case of intracerebral Non-Langerhans cell histiocytosis with review of the literature [PDF]

Diagnostic Pathology, 2007
Conclusion This case shows the unusual manifestation of a primary intracerebral Non-Langerhans cell histiocytosis, which begins as a solid mass around the sellar region and shows a remarkable extension as a flat lining of inner and outer liquor spaces.
Klaus Mueller, Mafalda Trippel, Ansgar Berlis, Wibke G. Janzarik, B Volk   +4 more
openalex   +5 more sources

Non-Langerhans cell histiocytosis in a child with Kawasaki disease

BMJ Case Reports, 2009
Polymorphous skin rashes are one of the major presentations in children with Kawasaki disease. This report describes an unusual presentation of a skin rash (non-Langerhans cell histiocytosis) in a 4-month-old baby with resistance to intravenous immunoglobulin (IVIG) treatment and coronary artery dilatation.
Ho‐Chang Kuo, Chia‐Che Wu, Ting Yang, Hong‐Ren Yu, Chun-Wei Liang, Yi‐Ju Chen, Kuender D. Yang   +6 more
openalex   +6 more sources