Results 1 to 10 of about 9,764 (249)

Case of Non-Langerhans Cell Histiocytosis in a Person Living with HIV - Clinical and Therapeutic Challenge [PDF]

Journal of the International Association of Providers of AIDS Care, 2022
Non-Langerhans cell histiocytosis is a rare disease which seldom affects adults. We report a case of a 32-year-old Bulgarian woman living with HIV. She developed severe anemia, extreme splenomegaly, requiring splenectomy and vertebral tumor formations ...
Nina Yancheva, Dimitar Strashimirov, Dragomir Dardanov, Bojidar Kamenov, Atanas Radinoff   +4 more
doaj   +6 more sources

Intermediate-dose cytarabine is an effective therapy for adults with non-Langerhans cell histiocytosis [PDF]

Orphanet Journal of Rare Diseases, 2022
Background Non-Langerhans cell histiocytosis, including Erdheim–Chester disease (ECD), Rosai–Dorfman disease (RDD), indeterminate cell histiocytosis (ICH), and unclassified histiocytosis, is a rare disorder lacking a standard treatment strategy.
Ting Liu, Hua-cong Cai, Hao Cai, Miao Chen, Wei Zhang, Jian Li, Dao-bin Zhou, Xin-xin Cao   +7 more
doaj   +4 more sources

Intra-arterial Melphalan for Neurologic Non-Langerhans Cell Histiocytosis. [PDF]

Neurology, 2021
Histiocytic neoplasms are rare hematologic disorders characterized by pathologic infiltration of activated histiocytes in affected tissues. The treatment of histiocytic neoplasms, including Langerhans cell histiocytosis (LCH) and non-LCH, has advanced in recent years owing to targeted kinase inhibitors (BRAF and MEK) as patients with somatic mutations ...
Francis JH, Gobin YP, Alshiekh Nasany R, Knopman J, Ulaner GA, Panageas KS, Hatzoglou V, Salvaggio K, Abramson DH, Patsalides A, Diamond EL.   +10 more
europepmc   +5 more sources

Successful Treatment of Non-Langerhans Cell Histiocytosis With Topical Rapamycin in Two Pediatric Cases [PDF]

Clinical, Cosmetic and Investigational Dermatology, 2022
Raden Mohamad Rendy Ariezal Effendi, Trustia Rizqandaru, Renata Yuliasari, Srie Prihianti Gondokaryono, Inne Arline Diana, Reiva Farah Dwiyana Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr.
Effendi RMRA, Rizqandaru T, Yuliasari R, Gondokaryono SP, Diana IA, Dwiyana RF   +5 more
doaj   +5 more sources

A Rare Case of Erdheim-Chester Disease (Non-Langerhans Cell Histiocytosis) with Concurrent Langerhans Cell Histiocytosis: A Diagnostic and Therapeutic Challenge [PDF]

Case Reports in Hematology, 2018
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocyte disorder most commonly characterized by multifocal osteosclerotic lesions of the long bones demonstrating sheets of foamy histiocyte infiltrates on biopsy with or without histiocytic ...
Hamza Hashmi, Drew Murray, John Greenwell, Marwan Shaikh, Soumit Basu, Maxwell Krem   +5 more
doaj   +6 more sources

High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis. [PDF]

Blood, 2017
Key Points Some 10.1% of adults with non–Langerhans cell histiocytosis have a concomitant myeloid neoplasm with each often harboring distinct mutations. The presence of distinct kinase mutations in histiocytosis and myeloid neoplasms resulted in discordant responses to targeted therapy.
Papo M, Diamond EL, Cohen-Aubart F, Emile JF, Roos-Weil D, Gupta N, Durham BH, Ozkaya N, Dogan A, Ulaner GA, Rampal R, Kahn JE, Sené T, Charlotte F, Hervier B, Besnard C, Bernard OA, Settegrana C, Droin N, Hélias-Rodzewicz Z, Amoura Z, Abdel-Wahab O, Haroche J.   +22 more
europepmc   +5 more sources

Synovial Non-langerhans Cell Histiocytosis of the Shoulder: A Case Report and Review of the Literature. [PDF]

J Orthop Case Rep, 2020
Histiocytoses are rare disorders and most orthopedic surgeons are unfamiliar with this diagnosis. We report a case of synovial non-Langerhans cell histiocytosis (LCH) located in the shoulder, which has not been reported in the literature previously.A 24-year-old female patient presented to our clinic with shoulder pain and decreased range of motion ...
Huri G, Çetik RM, Gedikoğlu G, Garbis N.   +3 more
europepmc   +5 more sources

Extensive reactive cutaneous histiocytic infiltrate resembling non-Langerhans cell histiocytosis as the presenting sign of underlying vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic syndrome. [PDF]

JAAD Case Rep, 2023
Wang CX, Yokoyama CC, Rosman IS, Musiek AC.   +3 more
europepmc   +2 more sources

PAPULAR HISTIOCYTOSIS OF HEAD : TYPE OF NON - LANGERHANS CELLS HISTIOCYTOSIS

Journal of Evolution of Medical and Dental Sciences, 2014
Papular histiocytosis of the head also known as benign cephalic histiocytosis is a rare, self-limiting histiocytosis that typically starts in early childhood. 1 Erythematous macules, papules and nodules develop on cheeks and spread to the forehead, earlobes and neck. Lesions are asymptomatic, gradually become reddish brown and may spread to involve the
Anil Kumar Gupta, Gaurav Murti
openalex   +2 more sources

Successful treatment of non-Langerhans cell histiocytosis with the MEK inhibitor trametinib: a multicenter analysis

Blood Advances, 2023
Abstract Erdheim-Chester disease (ECD) and Rosai-Dorfman disease (RDD) are rare non-Langerhans cell histiocytoses (non-LCHs), for which therapeutic options are limited. MAPK pathway activation through BRAFV600E mutation or other genomic alterations is a histiocytosis hallmark and correlates with a favorable response to BRAF inhibitors ...
Ashley Aaroe, Razelle Kurzrock, Gaurav Goyal, Aaron M. Goodman, Harsh Patel, Gordon Ruan, Gary A. Ulaner, Jason Young, Ziyi Li, Derek Dustin, Ronald S. Go, Eli L. Diamond, Filip Janku   +12 more
openalex   +3 more sources