Results 111 to 120 of about 4,423,036 (299)

(Non) Linear Regression Modeling [PDF]

open access: yes, 2011
We will study causal relationships of a known form between random variables. Given a model, we distinguish one or more dependent (endogenous) variables \(\mathbf{Y} = ({Y }_{1},\ldots,{Y }_{l}),l \in\mathbb{N}\), which are explained by a model, and independent (exogenous, explanatory) variables \(\mathbf{X} = ({X}_{1},\ldots,{X}_{p}),p \in\mathbb{N}\),
openaire   +1 more source

Testing non-linearity using a modified Q test [PDF]

open access: yes, 2012
A new version of the Q test, based on generalized residual correlations (i.e. auto-correlations and cross-correlations), is developed in this paper. The Q test fixes two main shortcomings of the Mcleod and Li Q (MLQ) test often used in the literature: (i)
Vavra, Marian
core  

Universal statistics of non-linear energy transfer in turbulent models

open access: yes, 1996
A class of shell models for turbulent energy transfer at varying the inter-shell separation, $\lambda$, is investigated. Intermittent corrections in the continuous limit of infinitely close shells ($\lambda \rightarrow 1$) have been measured.
B. Dubrulle   +24 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A Robust Non-Gaussian Data Assimilation Method for Highly Non-Linear Models

open access: yesAtmosphere, 2018
In this paper, we propose an efficient EnKF implementation for non-Gaussian data assimilation based on Gaussian Mixture Models and Markov-Chain-Monte-Carlo (MCMC) methods.
Elias D. Nino-Ruiz   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Dual Pairs of Gauged Linear Sigma Models and Derived Equivalences of Calabi-Yau threefolds

open access: yes, 2017
In this work we study the phase structure of skew symplectic sigma models, which are a certain class of two-dimensional N = (2,2) non-Abelian gauged linear sigma models.
Gerhardus, Andreas, Jockers, Hans
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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