Results 111 to 120 of about 1,160,851 (311)

Partially deorbitalized meta-GGA

open access: yesComputational Materials Today
Mejia-Rodriguez and Trickey recently proposed a procedure for removing the explicit dependence of meta-GGA exchange-correlation energy functionals Exc on the kinetic energy density τ.
P. Bonfà, S. Sharma, J.K. Dewhurst
doaj   +1 more source

A Novel Noise-Insensitive Chromatic Dispersion Estimation Method Based on Fractional Fourier Transform of LFM Signals

open access: yesIEEE Photonics Journal, 2017
We propose a novel chromatic dispersion (CD) estimation method by fractional Fourier transformation of linear-frequency modulation (LFM) signals. This method can measure inband and outband CD without using extra spectrum or timeslot resourses.
Wanli Wang   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Single Sr Atoms in Optical Tweezer Arrays for Quantum Simulation

open access: yesAtoms
We report on the realization of a platform for trapping and manipulating individual 88Sr atoms in optical tweezers. A first cooling stage based on a blue shielded magneto-optical trap (MOT) operating on the |1S0⟩→|1P1⟩ transition at 461 nm enables us to ...
Veronica Giardini   +8 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Acousto-optic deflectors in experimental neuroscience: overview of theory and applications

open access: yesJPhys Photonics
Cutting-edge methodologies and techniques are required to understand complex neuronal dynamics and pathological mechanisms. Among them, optical tools stand out due to their combination of non-invasiveness, speed, and precision.
Pietro Ricci   +5 more
doaj   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Frequency-bin entanglement-based Quantum Key Distribution

open access: yesnpj Quantum Information
Entanglement is an essential ingredient in many quantum communication protocols. In particular, entanglement can be exploited in quantum key distribution (QKD) to generate two correlated random bit strings whose randomness is guaranteed by the nonlocal ...
Noemi Tagliavacche   +7 more
doaj   +1 more source

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