Results 111 to 120 of about 369,770 (296)

Partially deorbitalized meta-GGA

Computational Materials Today
Mejia-Rodriguez and Trickey recently proposed a procedure for removing the explicit dependence of meta-GGA exchange-correlation energy functionals Exc on the kinetic energy density τ.
P. Bonfà, S. Sharma, J.K. Dewhurst
doaj   +1 more source

Emerging strategies to target metastasis and therapy resistance in melanoma

Molecular Oncology, EarlyView.
Emerging studies propose new approaches to interfere with melanoma progression. In recognition of melanoma awareness month, at Molecular Oncology, we highlight recently published research articles, focusing on novel therapeutic targets driving metastatic spread and outlining different strategies to overcome resistance to BRAF inhibitors and anti‐PD‐1 ...
Amel Aziba
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Single Sr Atoms in Optical Tweezer Arrays for Quantum Simulation

Atoms
We report on the realization of a platform for trapping and manipulating individual 88Sr atoms in optical tweezers. A first cooling stage based on a blue shielded magneto-optical trap (MOT) operating on the |1S0⟩→|1P1⟩ transition at 461 nm enables us to ...
Veronica Giardini, Luca Guariento, Andrea Fantini, Shawn Storm, Massimo Inguscio, Jacopo Catani, Giacomo Cappellini, Vladislav Gavryusev, Leonardo Fallani   +8 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Acousto-optic deflectors in experimental neuroscience: overview of theory and applications

JPhys Photonics
Cutting-edge methodologies and techniques are required to understand complex neuronal dynamics and pathological mechanisms. Among them, optical tools stand out due to their combination of non-invasiveness, speed, and precision.
Pietro Ricci, Giuseppe Sancataldo, Vladislav Gavryusev, Francesco Saverio Pavone, Peter Saggau, Martí Duocastella   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Frequency-bin entanglement-based Quantum Key Distribution

npj Quantum Information
Entanglement is an essential ingredient in many quantum communication protocols. In particular, entanglement can be exploited in quantum key distribution (QKD) to generate two correlated random bit strings whose randomness is guaranteed by the nonlocal ...
Noemi Tagliavacche, Massimo Borghi, Giulia Guarda, Domenico Ribezzo, Marco Liscidini, Davide Bacco, Matteo Galli, Daniele Bajoni   +7 more
doaj   +1 more source

Direct Generation and Non-Hermitian Regulation of Energy-Time-Polarization-Hyper-Entangled Quadphotons

Sensors
Entangled multiphoton is an ideal resource for quantum information technology. Here, narrow-bandwidth hyper-entangled quadphoton is theoretically demonstrated by quantizing degenerate Zeeman sub states through spontaneous eight-wave mixing (EWM) in a hot
Rui Zhuang, Siqiang Zhang, Guobin Liu, Zhou Feng, Qingyu Chen, Sinong Liu, Yanpeng Zhang   +6 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source