Results 81 to 90 of about 367,297 (292)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Buckling of Steel Portal Frames Considering Material Non-Linearity
Diyala Journal of Engineering Sciences, 2015 In this research, an experimental study was carried out to investigate the failure modes of eight frames with IPE cross-sections. The study was conducted by subjecting these frames to two equal concentrated loads (applied directly on columns); however ...
Orabi Al Rawi +2 more
doaj +1 more source
Solar-Terrestrial Data Science: Prior Experience and Future Prospects
Frontiers in Astronomy and Space Sciences, 2020 Acquisition of relatively large data sets based on measurements in the interplanetary medium, throughout Earth's magnetosphere, and from ground-based platforms has been a hallmark of the heliophysics discipline for several decades.
Daniel N. Baker
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Correcting the Non-Linear Response of Silicon Photomultipliers
SensorsThe finite number of pixels in a silicon photomultiplier (SiPM) limits its dynamic range to light pulses up to typically 80% of the total number of pixels in a device.
Lukas Brinkmann +3 more
doaj +1 more source
The Equivalent Gain Matrix of a Multivariable Non-Linearity
Measurement + Control, 1969 The equivalent gain concept of a mono-variable non-linear stochastic process is used to evaluate the linear matrix equivalent of a multi-variable non-linearity having n independent inputs and m outputs.
John C. West PhD, CEng, MIEE, MIEEE
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Light Readout of Small Scintillators Using SiPM Photosensors
SensorsDuring the last two decades, relevant progress has been achieved in silicon photomultiplier (SiPM) technology, such that in an increasing number of radiation detection applications they are proposed as a viable alternative to traditional photomultiplier ...
Chiara Rita Failla +3 more
doaj +1 more source
Non-Gaussianity vs. non-linearity of cosmological perturbations
, 2000 Following the discovery of the CMB, the hot big-bang model has become the standard cosmological model. In this theory, small primordial fluctuations are subsequently amplified by gravity to form the large-scale structure seen today.
Catelan +19 more
core +1 more source