Results 131 to 140 of about 223,220 (289)

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Low‐Dimensional Materials and Van Der Waals Heterostructures for Energy Application: A Comprehensive Review

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Low‐dimensional materials (0D, 1D, and 2D) exhibit unique electronic and physicochemical properties, enabling advanced nanoelectronic and optoelectronic devices. Mixed‐dimensional heterostructures combine these materials to enhance functionality.
Qaisar Alam, Sajjad Ali, Pir Muhammad Ismail, ABM Sharif Hossain   +3 more
wiley   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Metastatic Cutaneous Adnexal Carcinoma of the Head and Neck With Durable Response to an Aromatase Inhibitor Combined With a Cyclin‐Dependent Kinase 4/6 Inhibitor

Head &Neck, EarlyView.
ABSTRACT Background Cutaneous adnexal carcinomas are a very rare group of cancers arising from appendageal structures of the skin. More than half occur in the head and neck region. No standard treatments exist for metastatic disease. Methods A 48‐year‐old postmenopausal female presented with an enlarging scalp lesion.
Nilesh Kapoor, Manasa Narasimman, Travis Vandergriff, Amy L. Jones   +3 more
wiley   +1 more source

Prevention and early detection of the most aggressive skin cancer: melanoma

Quality in Sport
Skin cancers are the most common cancers and they are divided into two types: melanoma and non-melanoma skin cancers (NMSCs). Melanoma is the most lethal and aggressive type of skin cancer. The incidence of this type of cancer is increasing.
Agata Paulina Szostak, Kinga Szopińska, Magdalena Graca, Maria Janina Śmigielska-Mikołajczyk, Weronika Łowicka, Liliana Dyląg, Konrad Wawszkowicz, Karolina Oluszczak, Anna Szeliga, Karolina Korta   +9 more
doaj   +1 more source

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

Ibrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li, Ziba Ayi, Gonggong Lu, Haibo Rao, Feilong Yang, Jing Li, Jiachen Sun, Junlin Lu, Xulin Hu, Si Zhang, Xuhui Hui   +10 more
wiley   +1 more source

Long‐term association of physical activity with survival by primary cancer treatment in endometrial cancer: The Alberta Endometrial Cancer Cohort Study

International Journal of Cancer, EarlyView.
What's New? Accumulating evidence suggests a beneficial role of physical activity in cancer. However, it is unclear whether associations between physical activity and cancer outcomes vary by cancer treatment. Based on more than 16 years of follow‐up data from a cohort of endometrial cancer survivors, this study reveals that associations between ...
Minsuk Oh, Ki‐Yong An, Dong Hoon Lee, Renée L. Kokts‐Porietis, Linda S. Cook, Christine M. Friedenreich, Justin Y. Jeon, Kerry S. Courneya   +7 more
wiley   +1 more source

Real‐world effectiveness and safety with nivolumab plus ipilimumab or nivolumab alone in patients with or without melanoma brain metastasis: Results from the German noninterventional NICO study

International Journal of Cancer, EarlyView.
What's New? Although patients with melanoma brain metastases (MBM) may benefit from treatment with immune checkpoint inhibitors (ICIs), which are known to improve survival in advanced melanoma, MBM patients have often been excluded from trials evaluating ICIs.
Ralf Gutzmer, Michael Weichenthal, Thomas Eigentler, Peter Mohr, Thomas Sickmann, Pia Dücker, Christoffer Gebhardt, Sebastian Haferkamp, Katharina C. Kähler, Friedegund Meier, Claudia Pföhler, Anca Sindrilaru, Patrick Terheyden, Imke von Wasielewski, Selma Ugurel, Jens Ulrich, Jochen Utikal, Carsten Weishaupt, Dirk Schadendorf   +18 more
wiley   +1 more source

Dynamics of the association between circulating levels of miRNA and pancreatic cancer risk through the years prior to pancreatic cancer diagnosis

International Journal of Cancer, EarlyView.
What's New? Early diagnosis is critical for improving pancreatic ductal adenocarcinoma prognosis, but few biomarkers currently exist. In a case–control study of 1,307 pancreatic cancer cases and matched pairs nested in prospective cohort studies, 13 miRNA–cancer associations were found to change during the blood‐draw‐to‐diagnosis time window.
Hui Cai, Veronica Wendy Setiawan, Xingyi Guo, Jie Wu, Rachael Stolzenberg‐Solomon, Yu‐Tang Gao, Jordan Berlin, Fei Ye, Qiuyin Cai, Wei Zheng, Xiao‐Ou Shu   +10 more
wiley   +1 more source

Sensitive Period Analysis of Adulthood BMI and Cancer Risk: An Individual Participant Data Meta‐Analysis of Over 720,000 Participants in the ABACus 2 Consortium

International Journal of Cancer, EarlyView.
Over a dozen cancers have been associated with excess body mass index, primarily in mid‐to‐late adulthood. Whether obesity‐related cancer risk differs across adulthood remains unclear. Using the Sensitive Periods Model and super‐landmarking approaches, this study found that higher BMI increased obesity‐related cancer risk across ages 30–65.
Nadin K. Hawwash, Matthew Sperrin, Glen P. Martin, Rashmi Sinha, Charles E. Matthews, Matthias B. Schulze, Anouk Hiensch, Pilar Amiano, Marian L. Neuhouser, Corinne E. Joshu, Elizabeth A. Platz, Heinz Freisling, Marc J. Gunter, Andrew G. Renehan   +13 more
wiley   +1 more source