Results 111 to 120 of about 223,220 (289)
American Journal of Hematology, EarlyView.ABSTRACT Mycosis fungoides (MF) is a rare extranodal T‐cell lymphoma with primary cutaneous involvement. While it is the most common primary skin lymphoma, large‐scale real‐world data defining survival benchmarks and the prognostic significance of specific nodal sites remain limited.
Charalampos Filippatos +4 more
wiley +1 more source
Automatic segmentation of skin cancer images using adaptive color clustering [PDF]
, 2006 This paper presents the development of an adaptive image segmentation algorithm designed for the identification of the skin cancer and pigmented lesions in dermoscopy images. The key component of the developed algorithm is the Adaptive Spatial K-Means (A-
Ilea, Dana E., Whelan, Paul F.
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The 9th International RASopathies Symposium
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel +41 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman +15 more
wiley +1 more source
Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies
Animal Models and Experimental Medicine, EarlyView.This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang +4 more
wiley +1 more source
Starfished in the sand : developing the theory of planned behaviour to predict intentions to use sunscreen on the beach : a research project presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University, Albany, Auckland, New Zealand [PDF]
, 2003 This study examined the predictive power of the theory of planned behaviour in explaining sunscreen use intentions among beach-goers in New Zealand (n = 148) and the United Kingdom (n = 280). Generally, the theory of planned behaviour performed well with
Neil, Tessa Anne
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Humanized immune system animal models and their recent applications
Animal Models and Experimental Medicine, EarlyView.In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli +6 more
wiley +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Immune checkpoint inhibitors (ICIs) for cancer can lead to immune‐related adverse events, including ICI‐associated inflammatory arthritis (ICI‐IA). There are no validated International Classification of Diseases (ICD) code–based case definitions for ICI‐IA.
Manar Elsayed +11 more
wiley +1 more source
Skin Cancer Recognition using Deep Residual Network
, 2019 The advances in technology have enabled people to access internet from every part of the world. But to date, access to healthcare in remote areas is sparse. This proposed solution aims to bridge the gap between specialist doctors and patients.
Nagarajan, Dr. Sureshkumar, Rokad, Brij
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