Results 101 to 110 of about 13,440,667 (290)

skin cancer risk in renal transplant recipients

, 2021
With an increasing number of renal transplant recipients (RTRs) and improving patient survival, a higher incidence of non-melanoma skin cancer (NMSC) has been observed.
Zaw Thet, Dwarakanathan Ranganathan, Lam, Alfred K, Thin Han, Thet, Zaw, Aung, Soe Yu, Khoo, Tien K, Han, Thin, Soe Yu Aung, Ranganathan, Dwarakanathan, Alfred K. Lam, Tien K. Khoo   +11 more
core   +1 more source

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

Advanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran, Yanchun Fang, Shengming Ruan, Juling Wang, Songbai Liu, Yuan Mao, Dongsheng Hou, Yanping Wang, Zi Ye, Qiong Li, Daoxiang Zhang   +10 more
wiley   +1 more source

Skin Cancer Among Patients at a Major University Hospital in Saudi Arabia: A Retrospective, Single-Center Study

Clinical, Cosmetic and Investigational Dermatology
Abdossalam M Madkhali,1 Ghaida A Almarshoud,2 Layan F Alsanad,2 Rima Omar Alomar,2 Alia A Zawawi,2 Saud F Alrsheed,2 Sarah R Alaidarous,2 Bushra Alraddadi,3,4 Basel Bandar Almalki,4 Abdulaziz Madani4 1Department of Medicine, Oncology, Hematology and ...
Madkhali AM, Almarshoud GA, Alsanad LF, Alomar RO, Zawawi AA, Alrsheed SF, Alaidarous SR, Alraddadi B, Almalki BB, Madani A   +9 more
doaj  

Continuous Molecular Monitoring Using Electrochemical Aptamer‐Based Sensors: Remaining Challenges for Long‐Term In Vivo Deployment

Advanced Science, EarlyView.
Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley   +1 more source

A study on the global burden of non-melanoma skin cancer from 1990 to 2019

Introduction This study aimed to provide an overview and analysis of the global disease burden of non-melanoma skin cancer using data from the Global Burden of Disease 2019 (GBD 2019) database.
Jieya Ying, Yingli Zhou, Zixiang Si
core   +1 more source

Molecular and cellular pathogenesis of melanoma initiation and progression [PDF]

, 2013
Melanoma is a malignant tumour of melanocytes, which can spread to other organs of the body resulting in severe and/or lethal malignancies. Melanocytes are pigment producing cells found in deep layer of the epidermis and are originated from melanocytes ...
Regad, T
core   +1 more source

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

Advanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu, Juan Qin, Si‐Yuan Wu, Xue‐Zhen Zhu, Yun‐Fei Cai, Pei‐Yao Sun, Hao Yang, Xing‐Yue Wang, Shu Li, Duo Wang, Hai‐Dong Zhu   +10 more
wiley   +1 more source

The risk of skin cancer in women who carry BRCA1 or BRCA2 mutations

Hereditary Cancer in Clinical Practice
Background It has not been clearly established if skin cancer or melanoma are manifestations of BRCA1 or BRCA2 mutation carrier status. Estimating the risk of skin cancer is an important step towards developing screening recommendations.
Steven A. Narod, Kelly Metcalfe, Amy Finch, An-Wen Chan, Susan Randall Armel, Amber Aeilts, Andrea Eisen, Beth Karlan, Louise Bordeleau, Nadine Tung, William D. Foulkes, Susan L. Neuhausen, Charis Eng, Olufunmilayo Olopade, Dana Zakalik, Fergus Couch, Carey Cullinane, Tuya Pal, Ping Sun, Joanne Kotsopoulos, the Hereditary Breast Cancer Clinical Research Group   +20 more
doaj   +1 more source

Avaliação in vitro dos efeitos citotóxicos e antimetastáticos de sais de isotiourônio, de n-fenilisotiourônio e de isotiossemicarbazidas em linhagens de melanoma [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2014.O melanoma é um tipo de câncer de pele extremamente agressivo, devido à alta propensão em produzir ...
Cisilotto, Júlia
core  

Optimizing Cancer Vaccinations Using a Physiologically‐Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Model

Advanced Science, EarlyView.
Where and when should a cancer vaccine be administered? A whole‐body PBPK model demonstrates that systemic immune transport critically determines vaccination efficacy. By simulating how organ‐specific immune interactions influence treatment response, the study provides a quantitative framework for optimizing cancer vaccination strategies.
Mohammad R. Nikmaneshi, Timothy P. Padera, Lance L. Munn   +2 more
wiley   +1 more source