Results 41 to 50 of about 7,664,425 (315)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Blasting ore size detection based on efficient dehazing network and multi-dimensional feature fusion
Scientific ReportsOre particle size distribution is an important metric for evaluating blasting outcomes and affects the energy consumption of ore crushing equipment. Faced with dense accumulation of ore, nonuniform size distributions, dust occlusion, and target loss due ...
Pingfeng Li +6 more
doaj +1 more source
Adsorption of phosphate by cancrinite in red mud: a first-principles study
Materials Research Express, 2022 Cancrinite is the key substance that affects the adsorption effect of phosphate from red mud(RM) . Therefore, cancrinite in RM was modified to improve its adsorption performance. Based on density functional theory(DTF), this paper optimized the structure
Zhou Xiaotian +3 more
doaj +1 more source
Mining association rules for the quality improvement of the production process [PDF]
, 2013 Academics and practitioners have a common interest in the continuing development of methods and computer applications that support or perform knowledge-intensive engineering tasks.
Rigal, Fabien +2 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Scientific ReportsFatigue can cause human error, which is the main cause of accidents. In this study, the dynamic fatigue recognition of unmanned electric locomotive operators under high-altitude, cold and low oxygen conditions was studied by combining physiological ...
Shoukun Chen +8 more
doaj +1 more source
Metals, 2023 Low sensitivity to hot cracking is very important not only for casting but also for ingots of wrought alloys. Doping of Al-Cu-(Mg) alloys by eutectic forming elements provides an increasing resistance to hot cracking susceptibility, but it also leads to ...
Sayed M. Amer +6 more
doaj +1 more source
Ubiquitous data stream mining [PDF]
, 2004 The dissemination of data stream systems, wireless networks and mobile devices motivates the need for an efficient data analysis tool capable of gaining insights about these continuous data streams.
Zaslavsky, Arkady +5 more
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Effect of Sulfuric Acid Corrosion on Flotation Performance of Calcite by Changing Surface Roughness
MoleculesSurface roughness is a crucial factor that affects the flotation performance of minerals. In this study, the effect of sulfuric acid corrosion on the surface roughness of calcite flotation was investigated through microflotation tests, scanning electron ...
Dingquan Xing +5 more
doaj +1 more source