Association of peripheral inflammatory cytokines with motor and non-motor symptoms in patients with Parkinson's disease and type 2 diabetes mellitus. [PDF]
Hu A +9 more
europepmc +1 more source
Oligomeric alpha-synuclein causes early synaptic dysfunction of the corticostriatal pathway associated with non-motor symptoms. [PDF]
Bellingacci L +12 more
europepmc +1 more source
Evidence for the Link Between Non-Motor Symptoms, Kinematic Gait Parameters, and Physical Function in People with Parkinson's Disease. [PDF]
Timurtas E +4 more
europepmc +1 more source
Impact of istradefylline on motor and non-motor symptoms in patients with Parkinson's disease: Subanalysis of the ISTRA ADJUST PD. [PDF]
Nagayama H +28 more
europepmc +1 more source
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Non-motor symptoms: Identification and management
Parkinsonism & Related Disorders, 2007Non-motor symptoms are an important part of Parkinson's disease (PD) symptoms complex. They cause a significant burden on the quality of life of patients and their carers and remain a major cause of hospitalisation. Treatment of non-motor symptoms can be challenging as these symptoms are often unresponsive to conventional dopaminergic therapy. However,
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Alexithymia Is a Non-Motor Symptom of Parkinson Disease
The American Journal of Geriatric Psychiatry, 2012: To investigate whether alexithymia is linked to the disease process or to psychopathology, particularly depression, in Parkinson disease (PD) patients.: Cross-sectional study.: Neuropsychiatry outpatient clinic.: One hundred PD patients and 100 comparison subjects (CS).: PD patients and CS underwent a clinical and neuropsychiatric evaluation ...
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Non-motor symptoms in Parkinson's disease
Parkinsonism & Related Disorders, 2016With the growing awareness of the presence of non-motor symptoms in Parkinson's disease (PD) has come the realization that these non-motor features play a tremendously important, and sometimes dominant, role in the management and even the diagnosis of the disorder.
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The Burden of Non-Motor Symptoms
2011Although most of the symptoms of Parkinson’s disease (PD) seem to be motor-based, the non-motor symptoms (NMSs) of PD, often overshadowed, also constitute a major clinical challenge. The NMSs of PD, including neuropsychiatric, cognitive, gastrointestinal and sensory, not only are observed in later stages but also predominate in the early stages of PD ...
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Non‐motor symptoms in Parkinson’s disease
European Journal of Neurology, 2008Although still considered a paradigmatic movement disorder, Parkinson’s disease (PD) is associated with a broad spectrum of non‐motor symptoms. These include disorders of mood and affect with apathy, anhedonia and depression, cognitive dysfunction and hallucinosis, as well as complex behavioural disorders.
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Prevalence and features of non-motor symptoms in Wilson’s disease
Parkinsonism & Related Disorders, 2022Wilson's Disease (WD) is an autosomal recessive disorder caused by excessive copper deposition in liver, brain and other organs. The clinical picture is characterized by hepatic, psychiatric and neurological dysfunction. Movement disorders are the core neurological features, although non-motor symptoms (NMS), as cognitive/affective, autonomic and sleep
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