Results 171 to 180 of about 320,372 (214)

Oligomeric alpha-synuclein causes early synaptic dysfunction of the corticostriatal pathway associated with non-motor symptoms. [PDF]

open access: yesNPJ Parkinsons Dis
Bellingacci L   +12 more
europepmc   +1 more source

Impact of istradefylline on motor and non-motor symptoms in patients with Parkinson's disease: Subanalysis of the ISTRA ADJUST PD. [PDF]

open access: yesClin Park Relat Disord
Nagayama H   +28 more
europepmc   +1 more source

Non-motor symptoms: Identification and management

Parkinsonism & Related Disorders, 2007
Non-motor symptoms are an important part of Parkinson's disease (PD) symptoms complex. They cause a significant burden on the quality of life of patients and their carers and remain a major cause of hospitalisation. Treatment of non-motor symptoms can be challenging as these symptoms are often unresponsive to conventional dopaminergic therapy. However,
Muzerengi, Sharon   +2 more
openaire   +3 more sources

Alexithymia Is a Non-Motor Symptom of Parkinson Disease

The American Journal of Geriatric Psychiatry, 2012
: To investigate whether alexithymia is linked to the disease process or to psychopathology, particularly depression, in Parkinson disease (PD) patients.: Cross-sectional study.: Neuropsychiatry outpatient clinic.: One hundred PD patients and 100 comparison subjects (CS).: PD patients and CS underwent a clinical and neuropsychiatric evaluation ...
Assogna, F   +7 more
openaire   +4 more sources

Non-motor symptoms in Parkinson's disease

Parkinsonism & Related Disorders, 2016
With the growing awareness of the presence of non-motor symptoms in Parkinson's disease (PD) has come the realization that these non-motor features play a tremendously important, and sometimes dominant, role in the management and even the diagnosis of the disorder.
openaire   +2 more sources

The Burden of Non-Motor Symptoms

2011
Although most of the symptoms of Parkinson’s disease (PD) seem to be motor-based, the non-motor symptoms (NMSs) of PD, often overshadowed, also constitute a major clinical challenge. The NMSs of PD, including neuropsychiatric, cognitive, gastrointestinal and sensory, not only are observed in later stages but also predominate in the early stages of PD ...
Maria Joao Forjaz   +2 more
openaire   +1 more source

Non‐motor symptoms in Parkinson’s disease

European Journal of Neurology, 2008
Although still considered a paradigmatic movement disorder, Parkinson’s disease (PD) is associated with a broad spectrum of non‐motor symptoms. These include disorders of mood and affect with apathy, anhedonia and depression, cognitive dysfunction and hallucinosis, as well as complex behavioural disorders.
openaire   +2 more sources

Prevalence and features of non-motor symptoms in Wilson’s disease

Parkinsonism & Related Disorders, 2022
Wilson's Disease (WD) is an autosomal recessive disorder caused by excessive copper deposition in liver, brain and other organs. The clinical picture is characterized by hepatic, psychiatric and neurological dysfunction. Movement disorders are the core neurological features, although non-motor symptoms (NMS), as cognitive/affective, autonomic and sleep
Gianluigi Rosario Palmieri   +11 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy