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Non-motor symptoms in Parkinson’s disease [PDF]

open access: yesJournal of Neurology, 2009
Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease and is responsible for significant morbidity and costs. Non-motor manifestations of PD can be as disabling as the classic motor symptoms. Moreover, medications used to treat PD motor symptoms may have variable effects on these non-motor domains.
Ariane Park, Mark Stacy, Stacy Mark
exaly   +5 more sources

Identifying non-motor symptoms in Parkinson's disease and their connection with motor symptoms [PDF]

open access: yesСаратовский научно-медицинский журнал, 2016
The aim: the identification of patterns of formation and course of non-motor fluctuations in this disease and theirs connection with motor symptoms. Materials and Method, for realization of a research objective at 54 patients with Parkinson's disease ...
Poverennova I.E.   +2 more
doaj   +1 more source

Progression of motor symptoms in Parkinson’s disease [PDF]

open access: yesNeuroscience Bulletin, 2012
Parkinson's disease (PD) is a chronic progressive neurodegenerative disease that is clinically manifested by a triad of cardinal motor symptoms - rigidity, bradykinesia and tremor - due to loss of dopaminergic neurons. The motor symptoms of PD become progressively worse as the disease advances.
Ruiping Xia, Zhi-Hong Mao
exaly   +3 more sources

Efficacy and safety of adjunctive acupuncture for depression and motor symptoms in Parkinson’s disease: study protocol for a randomized controlled trial [PDF]

open access: yesFrontiers in Psychiatry
BackgroundDepression is one of the most prevalent and disabling non-motor symptoms in Parkinson’s disease (PD), forming a bidirectional relationship with motor dysfunction that worsens quality of life.
Kaihao Liao   +7 more
doaj   +2 more sources

MNCD: A New Tool for Classifying Parkinson’s Disease in Daily Clinical Practice

open access: yesDiagnostics, 2021
Background and objective: Parkinson’s disease (PD) is a clinically heterogeneous disorder in which the symptoms and prognosis can be very different among patients.
Diego Santos García   +15 more
doaj   +1 more source

Effects of Baduanjin Exercise on Rehabilitation of Patients With Mild to Moderate Parkinson’s Disease

open access: yesFrontiers in Neuroscience, 2022
ObjectivesRehabilitation, aerobic exercise, and many traditional Chinese exercises are known to significantly improve balance in patients with Parkinson’s disease.
Shuangshuang Dong   +10 more
doaj   +1 more source

Motor Symptoms and Schizophrenia [PDF]

open access: yesNeuropsychobiology, 2012
Classical schizophrenia literature reports motor symptoms as characteristic of the disorder. After the introduction of neuroleptic drugs, the existence of genuine motor disorders was challenged. Renewed interest arose as symptoms were found in never-medicated patients.
Walther, Sebastian, Strik, Werner
openaire   +3 more sources

Significant potential of melatonin therapy in Parkinson’s disease – a meta-analysis of randomized controlled trials

open access: yesFrontiers in Neurology, 2023
ObjectiveSince its discovery as an antioxidant, melatonin has been increasingly recognized for its therapeutic potential beyond sleep disturbances in neurodegenerative disorders.
Sadaf Iftikhar   +2 more
doaj   +1 more source

Cognitive impairment in Chinese patients with cervical dystonia

open access: yesFrontiers in Neurology, 2022
ObjectiveCognitive impairment (CI) in patients with cervical dystonia (CD) has been reported in many studies but with inconsistent findings. We investigated the prevalence, characteristics, and clinical factors related to CI in Chinese patients with CD ...
Kuncheng Liu   +7 more
doaj   +1 more source

Biomarkers and non-motor symptoms as a function of motor symptom asymmetry in early Parkinson's disease

open access: yesNeuropsychologia, 2022
The longitudinal trajectories of cognitive-neuropsychiatric symptoms from the early stages of Parkinson's disease, as a function of motor symptom asymmetry at the onset of the disease, remain to be fully explored. Moreover, the relationship to biomarkers warrants further investigation.Non-motor and biospecimen data from 413 patients with Parkinson's ...
Voruz, Philippe   +2 more
openaire   +3 more sources

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