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Non-motor symptoms in Parkinson’s disease [PDF]
Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease and is responsible for significant morbidity and costs. Non-motor manifestations of PD can be as disabling as the classic motor symptoms. Moreover, medications used to treat PD motor symptoms may have variable effects on these non-motor domains.
Ariane Park, Mark Stacy, Stacy Mark
exaly +5 more sources
Redefining Non-Motor Symptoms in Parkinson's Disease. [PDF]
Parkinson’s disease involves widespread neurodegeneration that extends far beyond the basal ganglia, giving rise to a diverse range of non-motor symptoms that frequently emerge before motor onset. These include autonomic dysfunction, cognitive decline, neuropsychiatric disturbances, sleep-related disorders, and sensory deficits.
Peña-Zelayeta L +9 more
europepmc +3 more sources
Non-Motor Symptoms Assessed by Non-Motor Symptoms Questionnaire and Non-Motor Symptoms Scale in Parkinson's Disease in Selected Asian Populations [PDF]
<b><i>Background:</i></b> Ethnic variations have been described in medical conditions, such as hypertension, diabetes, and multiple sclerosis. Whether ethnicity plays a role in Parkinson's disease (PD), particularly with regard to non-motor symptoms (NMS), remains unclear.
Sauerbier, Anna +16 more
openaire +3 more sources
Spectrum of Non-Motor Symptoms in Parkinson's Disease [PDF]
Parkinson's disease is predominantly classified as a movement disorder. Beyond the textbook definition of rigidity, tremors, and bradykinesia, Parkinson's disease encompasses an entire entity of non-motor symptom complexes that can precede the motor features by many years.
Kumaresan, Maithrayie, Khan, Safeera
openaire +2 more sources
Non-motor symptoms of Parkinson’s disease
Parkinson's disease is characterised by a complex array of motor and non-motor symptoms. Motor symptoms are often prioritised for assessment and treatment. Growing evidence highlights the importance of recognising the impact of non-motor symptoms on the person's quality of life.The aim of this article is to increase awareness of the importance of ...
Carroll, Vincent +2 more
openaire +3 more sources
Non-motor symptoms in cervical dystonia: A review
Dystonia is a movement disorder characterized by sustained or intermittent muscle contractions causing abnormal, often repetitive movements, postures, or both. Dystonic movements are typically patterned, associated with twisting of body parts, and may have tremulousness.
Somdattaa Ray +2 more
openaire +3 more sources
Sleep and non-motor symptoms in Parkinson’s disease [PDF]
Beyond the cardinal motor symptoms, bradykinesia, rigidity, tremor and postural instability, defining the diagnosis of Parkinson's disease, there is a big spectrum of non-motor features that patients may suffer from and that may reduce their quality of life.
Maass, Antonia, Reichmann, Heinz
openaire +2 more sources
Non-motor symptoms in amyotrophic lateral sclerosis
While motor symptoms are well-known in ALS, non-motor symptoms are often under-reported and may have a significant impact on quality of life. In this study, we aimed to examine the nature and extent of non-motor symptoms in ALS.A 20-item questionnaire was developed covering the domains of autonomic function, sleep, pain, gastrointestinal disturbance ...
Ali Shojaie +4 more
openaire +4 more sources
Non-motor symptoms in Parkinson's disease [PDF]
he classic features of the clinical picture in Parkinson’s disease (PD) are the motor disorders: akinesia, rigidity, tremor and postural instability. However, non-motor symptoms (NMS) are frequently present. Therefore, patients with PD can present, besides the typical parkinsonian motor syndrome, a wide arrow of NMS, mainly neuropsychiatric ...
openaire +3 more sources
Prodromal non-motor symptoms of Parkinson's disease [PDF]
The motor symptoms of Parkinson's disease (PD), bradykinesia, muscular rigidity, and tremor depend upon degeneration of the dopaminergic neurons in the substantia nigra pars compacta. Recent neuropathological studies show that the Lewy bodies, the intraneuronal landmark of PD, accumulate in several neuronal cell types in the brain.
PELLICANO, CLELIA +5 more
openaire +3 more sources

