Results 31 to 40 of about 320,284 (261)

Non-motor Symptoms of Parkinson's Disease

International Journal of Gerontology, 2007
In addition to the typical motor symptoms (resting tremor, cogwheel rigidity, bradykinesia, postural instability) of Parkinson's disease (PD), non-motor symptoms are sources of considerable burden in people with PD, espe-cially in elderly patients.
Jyh-Gong Gabriel Hou, Eugene C Lai
doaj   +1 more source

Longitudinal analysis of the Non-Motor Symptoms Scale in Parkinson's Disease (NMSS): An exploratory network analysis approach

Frontiers in Neurology, 2023
IntroductionParkinson's disease (PD) is a multisystem neurodegenerative disorder characterized by motor and non-motor symptoms. In particular, non-motor symptoms have become increasingly relevant to disease progression.
Konstantin G. Heimrich, Aline Schönenberg, Hannah M. Mühlhammer, Hannah M. Mühlhammer, Sarah Mendorf, Diego Santos-García, Tino Prell   +6 more
doaj   +1 more source

A Review of the Relationship Between Vitamin D and Parkinson Disease Symptoms

Frontiers in Neurology, 2020
Vitamin D is a fat-soluble secosteroid that exerts its effects by binding to the vitamin D receptor (VDR), through which it directly and indirectly modulates the expression of hundreds to thousands of genes.
Michelle E. Fullard, John E. Duda, John E. Duda   +2 more
doaj   +1 more source

Prodromal non-motor symptoms of Parkinson's disease [PDF]

Neuropsychiatric Disease and Treatment, 2007
The motor symptoms of Parkinson's disease (PD), bradykinesia, muscular rigidity, and tremor depend upon degeneration of the dopaminergic neurons in the substantia nigra pars compacta. Recent neuropathological studies show that the Lewy bodies, the intraneuronal landmark of PD, accumulate in several neuronal cell types in the brain.
PELLICANO, CLELIA, BENINCASA, DARIO, PISANI V, BUTTARELLI, Francesca Romana, GIOVANNELLI M, PONTIERI, FRANCESCO ERNESTO   +5 more
openaire   +3 more sources

Many Faces of Parkinson’s Disease: Non-Motor Symptoms of Parkinson’s Disease [PDF]

Journal of Movement Disorders, 2015
Parkinson’s disease (PD) is a multi-systemic disorder that is characterized by a combination of motor and non-motor symptoms (NMS). The dopaminergic neurodegeneration of PD is involved in the genesis of NMS, but other conditions and side effects of ...
Hye Mi Lee, Seong-Beom Koh
doaj   +1 more source

Identifying non-motor symptoms in Parkinson's disease and their connection with motor symptoms [PDF]

Саратовский научно-медицинский журнал, 2016
The aim: the identification of patterns of formation and course of non-motor fluctuations in this disease and theirs connection with motor symptoms. Materials and Method, for realization of a research objective at 54 patients with Parkinson's disease ...
Poverennova I.E., Kalinin V.A., Muchina S.A.   +2 more
doaj  

Parkinson's Disease Subtypes Identified from Cluster Analysis of Motor and Non-motor Symptoms

Frontiers in Aging Neuroscience, 2017
Parkinson's disease is now considered a complex, multi-peptide, central, and peripheral nervous system disorder with considerable clinical heterogeneity. Non-motor symptoms play a key role in the trajectory of Parkinson's disease, from prodromal premotor
Jesse Mu, Kallol R. Chaudhuri, Concha Bielza, Jesus de Pedro-Cuesta, Pedro Larrañaga, Pablo Martinez-Martin   +5 more
doaj   +1 more source

Retrospective analysis of diet and gut microbiota diversity and clinical pharmacology outcomes in patients with Parkinsonism syndrome

Heliyon
Background: Parkinson's disease (PD) is a global neurodegenerative ailment impacting millions, causes significant degeneration of dopaminergic neurons in the substantia nigra. Emerging research underscores the gut microbiota's role in PD onset.
Yunxin Hu, Haoyue Wang, Yongkang Zhong, Yongqi Sun   +3 more
doaj   +1 more source

Serum neurotransmitter analysis of motor and non-motor symptoms in Parkinson's patients. [PDF]

Front Aging Neurosci
Fan Y, Yang W, Wu W, Wang X, Lin Y, Wu L, Wang J, Huan F, Ding H, Gao R.   +9 more
europepmc   +2 more sources

Non-motor symptoms in parkinson’s disease [PDF]

Саратовский научно-медицинский журнал, 2012
<p>The goal of the research was to investigate some non-motor disorders at patients with Parkinson disease (PD) and to determine their relations to the main manifestations of the disease. 68 patients with PD without dementia were studied.
Baidina T.V., Torgan T.I.
doaj