Results 51 to 60 of about 654,324 (304)

Retrospective analysis of diet and gut microbiota diversity and clinical pharmacology outcomes in patients with Parkinsonism syndrome

Heliyon
Background: Parkinson's disease (PD) is a global neurodegenerative ailment impacting millions, causes significant degeneration of dopaminergic neurons in the substantia nigra. Emerging research underscores the gut microbiota's role in PD onset.
Yunxin Hu, Haoyue Wang, Yongkang Zhong, Yongqi Sun   +3 more
doaj   +1 more source

Spotlight on non-motor symptoms and Covid-19

, 2022
The Coronavirus Disease 2019 (Covid-19) pandemic has profoundly affected the quality of life (QoL) and health of the general population globally over the past 2 years, with a clear impact on people with Parkinson's Disease (PwP, PD). Non-motor symptoms have been widely acknowledged to hold a vital part in the clinical spectrum of PD, and, although ...
Rota, Silvia, Boura, Iro, Wan, Yi Min, Lazcano-Ocampo, Claudia, Rodriguez-Violante, Mayela, Antonini, Angelo, Chaudhuri, Kallol Ray   +6 more
openaire   +3 more sources

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Behavioral characterization of the 6-hydroxidopamine model of Parkinson's disease and pharmacological rescuing of non-motor deficits [PDF]

, 2013
BACKGROUND: Parkinson's disease (PD) is a chronic neurodegenerative condition that is characterized by motor symptoms as a result of dopaminergic degeneration, particularly in the mesostriatal pathway.
Ana J Rodrigues, António J Salgado, Bárbara Coimbra, Carla Rodrigues, Filipa L Campos, José M Pêgo, Miguel M Carvalho, Nuno Sousa, Rui Lima   +8 more
core   +1 more source

Effects of tai chi on postural control during dual-task stair negotiation in knee osteoarthritis : a randomised controlled trial protocol [PDF]

, 2020
Stair ascent and descent require complex integration between sensory and motor systems; individuals with knee osteoarthritis (KOA) have an elevated risk for falls and fall injuries, which may be in part due to poor dynamic postural control during ...
Chang, A, Chen, B, Chen, S, Fu, S, Hou, M, Li, Z, Liu, A, Qi, D, Wang, X, Xie, X, Xiong, F, Yang, F, Yu, J, Zhang, Y   +13 more
core   +2 more sources

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Multidimensional Factors Can Explain the Clinical Worsening in People With Parkinson's Disease During the COVID-19 Pandemic: A Multicenter Cross-Sectional Trial

Frontiers in Neurology, 2021
Background: Self-reported clinical worsening by people with Parkinson's disease (PD) during social distancing may be aggravated in Brazil, where the e/tele-health system is precarious.Objectives: This study aims to investigate self-reported changes in ...
Carla Silva-Batista, Daniel Boari Coelho, Renato Campos Freire Júnior, Lorena Rosa Almeida, Lorena Rosa Almeida, Adriana Guimarães, Katia Cirilo Costa Nóbrega, Hugo Machado Sanchez, Ana Raquel Rodrigues Lindquist, Vera Lúcia Israel, Hélcio Kanegusuku, Rachel Guimarães, Nayanne Beckmann Bosaipo, Richelma Barbosa, Clynton Lourenço Correa, Maria José Finatto, Felipe Augusto dos Santos Mendes, Maria Elisa Pimentel Piemonte   +17 more
doaj   +1 more source

Non-Motor Off Symptoms in Parkinson's Disease

Journal of Korean Medical Science, 2009
The aim of this study is to elucidate the clinical spectrum and frequency of non-motor symptoms during off periods (NMOS) in Parkinson's disease (PD) patients with motor fluctuation. We compared clinical characteristics between PD patients with motor symptoms only (M-off) and those with both motor and non-motor symptoms (NM-off) during off periods. The
Cheon, Sang-Myung, Park, Min Jeong, Kim, Wook-Joo, Kim, Jae Woo   +3 more
openaire   +2 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Factors Contributing to Malnutrition in Parkinson's Disease Patients With Freezing of Gait

Frontiers in Neurology, 2022
Background and PurposeLittle is known about the nutritional status and clinical characteristics of patients with Parkinson's disease with freezing of gait (PDFOG).
Li-Li Zhang, Li-Li Zhang, Li-Li Zhang, Liang Zhang, Jingde Dong, Ying Zhao, Xiao-Ping Wang   +6 more
doaj   +1 more source