Results 51 to 60 of about 12,797,283 (292)

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques, Mariana dos Santos Murra, Welinton Hirai, Ana Laura Balduino do Nascimento, Karla Emilia de Sá Rodrigues, Wilson Elias de Oliveira Junior   +5 more
wiley   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

Non-motor symptoms in motor neuron disease:Prevalence, assessment and impact [PDF]

People with motor neuron disease often experience non-motor symptoms that may occur secondary to, or distinct from, motor degeneration and that may significantly reduce quality of life, despite being under-recognized and evaluated in clinical practice ...
Newton, Judith, Johnson, Micheala, Abrahams, Sharon, Carson, Alan, Glasmacher, Stella, Dakin, Rachel, Beswick, Emily, Chandran, Siddharthan, Forbes, Deborah, Pal, Suvankar; id_orcid   +9 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Non-Motor Symptoms of Parkinson's Disease: Diagnosis and Management [PDF]

, 2010
Non-motor symptoms (NMS) of Parkinson's disease (PD) are a key determinant of health, quality of life (QoL) and societal cost of PD. They are often less appreciated than motor symptoms but are importantsources of disability for manyPDpatients. Literature
AB Olokoba, Salawu, FK, Olokoba, AB, A Danburam, Danburam, A, FK Salawu   +5 more
core   +1 more source

Frequency of Non-motor Symptoms in Parkinson's Patients With Motor Fluctuations

Frontiers in Neurology, 2021
Background: Non-motor symptoms (NMS), including neuropsychiatric, sleep, autonomic, and sensory domains, are an integral aspect of the clinical presentation of Parkinson disease (PD) and affect neurocognitive functioning as well as patients' and ...
Mariana Fernandes, Mariangela Pierantozzi, Mariangela Pierantozzi, Alessandro Stefani, Alessandro Stefani, Carlo Cattaneo, Erminio A. Bonizzoni, Rocco Cerroni, Nicola Biagio Mercuri, Nicola Biagio Mercuri, Claudio Liguori, Claudio Liguori, Claudio Liguori   +12 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Treatment Options for Motor and Non-Motor Symptoms of Parkinson’s Disease

Biomolecules, 2021
Parkinson’s disease (PD) usually presents in older adults and typically has both motor and non-motor dysfunctions. PD is a progressive neurodegenerative disorder resulting from dopaminergic neuronal cell loss in the mid-brain substantia nigra pars ...
Frank C. Church
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Orthostatic hypotension in Parkinson’s disease: effects on clinical features and disease severity-a systematic review and meta-analysis

Frontiers in Aging Neuroscience
BackgroundParkinson’s disease (PD) is often associated with orthostatic hypotension (OH). However, research examining the relationship between OH and PD has yielded inconsistent results.
Hui Wang, Chi Zhang, Dongxun Xu
doaj   +1 more source