Results 21 to 30 of about 12,797,283 (292)

Role of GABA pathway in motor and non-motor symptoms in Parkinson's disease: a bidirectional circuit

European Journal of Medical Research
Parkinson's disease (PD) is a progressive neurodegenerative disease as a result of the degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The fundamental features of PD are motor and non-motor symptoms. PD symptoms develop
Bandar Alharbi, Hayder M. Al-kuraishy, Ali I. Al-Gareeb, Engy Elekhnawy, Hind Alharbi, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batiha   +7 more
doaj   +3 more sources

Non-Motor Symptoms Assessed by Non-Motor Symptoms Questionnaire and Non-Motor Symptoms Scale in Parkinson's Disease in Selected Asian Populations [PDF]

Neuroepidemiology, 2017
<b><i>Background:</i></b> Ethnic variations have been described in medical conditions, such as hypertension, diabetes, and multiple sclerosis. Whether ethnicity plays a role in Parkinson's disease (PD), particularly with regard to non-motor symptoms (NMS), remains unclear.
Sauerbier, Anna, Jitkritsadakul, Onanong, Titova, Nataliya, Klingelhoefer, Lisa, Tsuboi, Yoshio, Carr, Harry, Kumar, Hrishikesh, Banerjee, Rebecca, Erro, Roberto, Bhidayasiri, Roongroj, Schrag, Anette, Zis, Panagiotis, Lim, Shen-Yang, Al-Hashel, J. Y., Kamel, Walaa A., Martinez-Martin, Pablo, Ray Chaudhuri, K.   +16 more
openaire   +3 more sources

Non-motor symptoms of Parkinson’s disease

Australian Journal of General Practice, 2021
Parkinson's disease is characterised by a complex array of motor and non-motor symptoms. Motor symptoms are often prioritised for assessment and treatment. Growing evidence highlights the importance of recognising the impact of non-motor symptoms on the person's quality of life.The aim of this article is to increase awareness of the importance of ...
Carroll, Vincent, Rossiter, Rachel, Blanchard, Denise   +2 more
openaire   +3 more sources

Spectrum of Non-Motor Symptoms in Parkinson's Disease [PDF]

Cureus, 2021
Parkinson's disease is predominantly classified as a movement disorder. Beyond the textbook definition of rigidity, tremors, and bradykinesia, Parkinson's disease encompasses an entire entity of non-motor symptom complexes that can precede the motor features by many years.
Kumaresan, Maithrayie, Khan, Safeera
openaire   +2 more sources

Non-motor symptoms in cervical dystonia: A review

Annals of Indian Academy of Neurology, 2020
Dystonia is a movement disorder characterized by sustained or intermittent muscle contractions causing abnormal, often repetitive movements, postures, or both. Dystonic movements are typically patterned, associated with twisting of body parts, and may have tremulousness.
Somdattaa Ray, Pramod Kumar Pal, Ravi Yadav   +2 more
openaire   +3 more sources

Non-motor symptoms in amyotrophic lateral sclerosis: lessons from Parkinson’s disease [PDF]

, 2023
Amyotrophic lateral sclerosis and Parkinson’s disease are neurodegenerative diseases of the motor system which are now recognized also to affect non-motor pathways. Non-motor symptoms have been acknowledged as important determinants of quality of life in
Ali Shojaie, Chaudhuri, K, Ahmad Al Khleifat, Shojaie, Ali, Rota, Silvia, K Ray Chaudhuri, Ammar Al-Chalabi, Al Khleifat, Ahmad; id_orcid, Al-Chalabi, Ammar, Silvia Rota   +9 more
core   +1 more source

Non-motor symptoms in Parkinson's disease [PDF]

Arquivos de Neuro-Psiquiatria, 2013
he classic features of the clinical picture in Parkinson’s disease (PD) are the motor disorders: akinesia, rigidity, tremor and postural instability. However, non-motor symptoms (NMS) are frequently present. Therefore, patients with PD can present, besides the typical parkinsonian motor syndrome, a wide arrow of NMS, mainly neuropsychiatric ...
openaire   +3 more sources

Sleep and non-motor symptoms in Parkinson’s disease [PDF]

Journal of Neural Transmission, 2013
Beyond the cardinal motor symptoms, bradykinesia, rigidity, tremor and postural instability, defining the diagnosis of Parkinson's disease, there is a big spectrum of non-motor features that patients may suffer from and that may reduce their quality of life.
Maass, Antonia, Reichmann, Heinz
openaire   +2 more sources

A Review of the Relationship Between Vitamin D and Parkinson Disease Symptoms

Frontiers in Neurology, 2020
Vitamin D is a fat-soluble secosteroid that exerts its effects by binding to the vitamin D receptor (VDR), through which it directly and indirectly modulates the expression of hundreds to thousands of genes.
Michelle E. Fullard, John E. Duda, John E. Duda   +2 more
doaj   +1 more source

Digital health technology for non-motor symptoms in people with Parkinson's disease Futile or future?

, 2021
Introduction: There is an ongoing digital revolution in the field of Parkinson's disease (PD) for the objective measurement of motor aspects, to be used in clinical trials and possibly support therapeutic choices.
Trivedi, Dhaval,, The International Parkinson and Movement Disorder Society Non Motor Parkinson's Disease Study Group, Lund University.   +2 more
core   +1 more source