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Non-motor symptoms: Identification and management
Parkinsonism & Related Disorders, 2007Non-motor symptoms are an important part of Parkinson's disease (PD) symptoms complex. They cause a significant burden on the quality of life of patients and their carers and remain a major cause of hospitalisation. Treatment of non-motor symptoms can be challenging as these symptoms are often unresponsive to conventional dopaminergic therapy. However,
Muzerengi, Sharon +2 more
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Alexithymia Is a Non-Motor Symptom of Parkinson Disease
The American Journal of Geriatric Psychiatry, 2012: To investigate whether alexithymia is linked to the disease process or to psychopathology, particularly depression, in Parkinson disease (PD) patients.: Cross-sectional study.: Neuropsychiatry outpatient clinic.: One hundred PD patients and 100 comparison subjects (CS).: PD patients and CS underwent a clinical and neuropsychiatric evaluation ...
Assogna, F +7 more
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Non‐motor symptoms in Parkinson’s disease
European Journal of Neurology, 2008Although still considered a paradigmatic movement disorder, Parkinson’s disease (PD) is associated with a broad spectrum of non‐motor symptoms. These include disorders of mood and affect with apathy, anhedonia and depression, cognitive dysfunction and hallucinosis, as well as complex behavioural disorders.
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Non-motor symptoms in Parkinson's disease
Parkinsonism & Related Disorders, 2016With the growing awareness of the presence of non-motor symptoms in Parkinson's disease (PD) has come the realization that these non-motor features play a tremendously important, and sometimes dominant, role in the management and even the diagnosis of the disorder.
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The heterogeneity of non-motor symptoms of Parkinson’s disease
Neurological Sciences, 2014In addition to motor symptoms, patients with Parkinson's disease (PD) may experience non-motor symptoms (NMS), more often with more advanced disease stage. However, the clinical feature of the NMS and potential risk factors that affect NMS in idiopathic PD patients remain unclear. 493 PD patients diagnosed with PD via the UK.
Ning, Zhang +4 more
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Prevalence and features of non-motor symptoms in Wilson’s disease
Parkinsonism & Related Disorders, 2022Wilson's Disease (WD) is an autosomal recessive disorder caused by excessive copper deposition in liver, brain and other organs. The clinical picture is characterized by hepatic, psychiatric and neurological dysfunction. Movement disorders are the core neurological features, although non-motor symptoms (NMS), as cognitive/affective, autonomic and sleep
Gianluigi Rosario Palmieri +11 more
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[Non-motor symptoms of Parkinson's disease].
Nederlands tijdschrift voor geneeskunde, 2012Parkinson's disease has traditionally been viewed as a disease with only motor features. Nowadays, a wide variety of non-motor symptoms and signs are also recognised as being characteristic of the disease. Non-motor symptoms, most importantly autonomic dysfunction, neuropsychiatric symptoms and sleep problems, are prevalent in virtually all Parkinson's
Weerkamp, N.J., Nijhof, A., Tissingh, G.
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The Burden of Non-Motor Symptoms
2011Although most of the symptoms of Parkinson’s disease (PD) seem to be motor-based, the non-motor symptoms (NMSs) of PD, often overshadowed, also constitute a major clinical challenge. The NMSs of PD, including neuropsychiatric, cognitive, gastrointestinal and sensory, not only are observed in later stages but also predominate in the early stages of PD ...
Maria Joao Forjaz +2 more
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Parkinson’s disease: a review of non-motor symptoms
Expert Review of Neurotherapeutics, 2015Parkinson's disease (PD) is a neurodegenerative disorder resulting from degeneration of the substantia nigra and the dopaminergic nigrostriatal pathway. Most treatments are geared toward the management and relief of motor symptoms in Parkinson's patients; however, as the disease progresses, various complications can be observed. Non-motor symptoms (NMS)
Abdul Qayyum, Rana +3 more
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Overlooked non-motor symptoms in myasthenia gravis
Journal of Neurology, Neurosurgery & Psychiatry, 2012Patients with myasthenia gravis (MG) may have various non-motor symptoms in addition to fatigability and weakness of skeletal muscles. Thymomas contain abundant immature thymocytes and developing CD4 and CD8 T cells. Thymomas are found in 15-25% of patients with MG and are associated with severe symptoms. We suggest that non-motor symptoms are based on
Shigeaki, Suzuki +2 more
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