Results 31 to 40 of about 11,033 (182)

Preoperative caudal blocks associated with decreased cumulative opioid requirements compared to postoperative caudal blocks in pediatric urologic surgery

UroPrecision, EarlyView.
Abstract Background Caudal blocks (CB) are a cornerstone of pediatric urologic surgery, providing effective analgesia while mitigating potential neurotoxicity associated with general anesthesia and opioids. However, the optimal timing of CB—preoperative versus postoperative—remains controversial.
Jordan L. Mendelson, William Brenseke, Diego Alvarez Vega, William Nguyen, Mohammed Shium, Saige Gitlin, Ronnie G. Fine, Steven C. Friedman, Mark Horowitz, Walter I. Weiss, Raghu Idupuganti, Jordan S. Gitlin   +11 more
wiley   +1 more source

POTENT NON-NARCOTIC ANALGESICS AS А DIRECTION IN DEVELOPMENT OF PHARMACEUTICALS

Разработка и регистрация лекарственных средств, 2019
The article describes some approaches to choice of the most potent non-narcotic analgesics among agents investigated in various R&D stages. Preparations non-narcotic analgesics for relief of severe and moderate pain are relatively new area of ...
A. V. Sosnov, S. V. Sadovnikov, F. M. Semchenko, K. A. Rufanov, V. N. Tohmahchi, A. A. Sosnova, I. A. Tyurin   +6 more
doaj  

Opioid-free anesthesia for breast cancer surgery: An observational study

Journal of Anaesthesiology Clinical Pharmacology, 2018
Background and Aims: Opioids are associated with postoperative nausea, vomiting, drowsiness, and increased analgesic requirement. A nonopioid anesthesia technique may reduce morbidity, enable day care surgery, and possibly decrease tumor recurrence.
Swagata Tripathy, Satyajit Rath, Suresh Agrawal, P Bhaskar Rao, A Panda, T S Mishra, Sukdev Nayak   +6 more
doaj   +1 more source

Insights from a six‐year hair drug analysis compendium in drug‐facilitated crimes involving vulnerable population cases

Journal of Forensic Sciences, EarlyView.
Abstract Hair analysis is a well‐established matrix in forensic toxicology, offering a valuable alternative or complement to traditional matrices in diverse contexts, including drug‐facilitated crimes (DFC), elder abuse, and accidental exposure in children.
Amandine Fort, Coralie Boudin, Hélène Eysseric‐Guerin, Virginie Scolan, François Paysant, Cloé Scherpereel, Mélissa Revet, Françoise Stanke‐Labesque, Théo Willeman   +8 more
wiley   +1 more source

Investigation of eosin Y as a colorimetric sensor for the detection of fentanyl hydrochloride and fentanyl freebase

Journal of Forensic Sciences, EarlyView.
Abstract The increasing prevalence of fentanyl within the illegal global drug market underscores the need for rapid, low‐cost, and straightforward detection methods. Eosin Y demonstrates a measurable color change in the presence of fentanyl, making it a promising candidate for colorimetric sensing and preliminary identification of fentanyl ...
Alan J. Zhou, Melissa M. Dixon, Brady S. Gentle, Genevieve H. Dennison, Kellie L. Tuck   +4 more
wiley   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

The role of ketorolac in the accelerated rehabilitation program for patients in outpatient surgery

Амбулаторная хирургия, 2019
The paper presents the basic principles of accelerated reabiletacii patient in the practice of ambulatory surgery. Pathophysiological mechanisms  revealed  organism  response   to  surgical  trauma.   Pain,  as  a  powerful  trigger  of  surgical  stress 
B. K. Vandanov, N. N. Lebedev, A. N. Shikhmetov   +2 more
doaj   +1 more source

Opioid-free anesthesia for a child with trisomy 13 with obstructive sleep apnea: a case report

JA Clinical Reports, 2020
Background Most children with trisomy 13 display central apnea, and are prone to opioid-induced respiratory depression. We conducted opioid-free anesthesia for a patient with trisomy 13 and obstructive sleep apnea, and safely extubated the patient in the
Makiko Yamamoto, Izumi Miyazaki, Hiroaki Kishikawa, Atsuhiro Sakamoto   +3 more
doaj   +1 more source

Physiological and behavioural effects of continuous remifentanil‐xylazine administration in donkeys

Equine Veterinary Journal, EarlyView.
Abstract Background Remifentanil and xylazine are used as continuous infusions to facilitate standing surgery in horses. Their use for this purpose has not been reported in donkeys. Objectives To evaluate the behavioural, sedative, and cardiorespiratory effects of continuous intravenous infusion of remifentanil and xylazine in donkeys. Study Design Non‐
Kássia Fernanda Araújo Damasceno, Andressa Nunes Mouta, Larissa de Sant' Ana Alves, Kathryn Nóbrega Arcoverde, Herbert Reis Aragão, Jerson Marques Cavalcante, Valéria Veras de Paula   +6 more
wiley   +1 more source

Efficacy of Paracetamol Plus Lignocaine versus Lignocaine Alone for Pain on Propofol Injection: A Randomised Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Propofol triggers endothelial irritation and nociceptor activation, producing early injection pain. Lignocaine blunts this response but does not abolish it completely. A brief systemic analgesic may help close this residual gap.
Jyotsna Rhea Dass , Kunda Dimble, Naseema Kanase, Meela Ranjith Kumar   +3 more
doaj   +1 more source