Results 41 to 50 of about 1,535 (215)

MCA-NMF: Multimodal Concept Acquisition with Non-Negative Matrix Factorization. [PDF]

open access: yesPLoS ONE, 2015
In this paper we introduce MCA-NMF, a computational model of the acquisition of multimodal concepts by an agent grounded in its environment. More precisely our model finds patterns in multimodal sensor input that characterize associations across ...
Olivier Mangin   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Onto Proximality in Non Negative Matrix Factorization for Recommender Systems

open access: yesIEEE Access
Recommender Systems have become integral to most e-commerce applications and online platforms. The recommended suggestions heavily impact customer retention and business performance.
Rachana Mehta   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Multi-constraint non-negative matrix factorization for community detection: orthogonal regular sparse constraint non-negative matrix factorization

open access: yesComplex & Intelligent Systems
Community detection is an important method to analyze the characteristics and structure of community networks, which can excavate the potential links between nodes and further discover subgroups from complex networks.
Zigang Chen   +6 more
doaj   +1 more source

Infinite Non-Negative Matrix Factorization

open access: yes, 2010
Publication in the conference proceedings of EUSIPCO, Aalborg, Denmark ...
Mikkel N. Schmidt, Morten Mørup
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Semantic Non-Negative Matrix Factorization for Term Extraction

open access: yesBig Data and Cognitive Computing
This study introduces an unsupervised term extraction approach that combines non-negative matrix factorization (NMF) with word embeddings. Inspired by a pioneering semantic NMF method that employs regularization to jointly optimize document–word and word–
Aliya Nugumanova   +4 more
doaj   +1 more source

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