Results 61 to 70 of about 1,535 (215)

Muscle Synergy during Wrist Movements Based on Non-Negative Tucker Decomposition

open access: yesSensors
Modular control of the muscle, which is called muscle synergy, simplifies control of the movement by the central nervous system. The purpose of this study was to explore the synergy in both the frequency and movement domains based on the non-negative ...
Xiaoling Chen   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Robust Hierarchical Learning for Non-Negative Matrix Factorization With Outliers

open access: yesIEEE Access, 2019
Desirable properties of extensions of non-negative matrix factorization (NMF) include robustness in the presence of noises and outliers, ease of implementation, the guarantee of convergence, operation in an automatic fashion that trades off the balance ...
Yinan Li   +4 more
doaj   +1 more source

Non-negative Matrix Factorization for Binary Data

open access: yesProceedings of the 7th International Joint Conference on Knowledge Discovery, Knowledge Engineering and Knowledge Management, 2015
We propose the Logistic Non-negative Matrix Factorization for decomposition of binary data. Binary data are frequently generated in e.g. text analysis, sensory data, market basket data etc. A common method for analysing non-negative data is the Non-negative Matrix Factorization, though this is in theory not appropriate for binary data, and thus we ...
Jacob Søgaard Larsen   +1 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Multi-Focus Image Fusion Based on WNMF and Focal Point Position Analysis

open access: yes工程科学与技术, 2011
:In this paper, a multi-focus image fusion method based on the weighted non-negative matrix factorization is presented to improve image fusion method based on non-negative matrix factorization.
A Du Jian Hua
doaj  

A New Feature Extraction and Recognition Method for Microexpression Based on Local Non-negative Matrix Factorization

open access: yesFrontiers in Neurorobotics, 2020
Microexpression is usually characterized by short duration and small action range, and the existing general expression recognition algorithms do not work well for microexpression.
Junli Gao   +4 more
doaj   +1 more source

Topic supervised non-negative matrix factorization

open access: yesCoRR, 2017
Topic models have been extensively used to organize and interpret the contents of large, unstructured corpora of text documents. Although topic models often perform well on traditional training vs. test set evaluations, it is often the case that the results of a topic model do not align with human interpretation.
MacMillan, K., Wilson, James D
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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