Results 71 to 80 of about 53,454 (335)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Infinite Non-Negative Matrix Factorization

, 2010
Publication in the conference proceedings of EUSIPCO, Aalborg, Denmark ...
Mikkel N. Schmidt, Morten Mørup
openaire   +3 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Onto Proximality in Non Negative Matrix Factorization for Recommender Systems

IEEE Access
Recommender Systems have become integral to most e-commerce applications and online platforms. The recommended suggestions heavily impact customer retention and business performance.
Rachana Mehta, Shakti Mishra, Snehanshu Saha   +2 more
doaj   +1 more source

Semi-Supervised Projective Non-Negative Matrix Factorization for Cancer Classification. [PDF]

PLoS ONE, 2015
Advances in DNA microarray technologies have made gene expression profiles a significant candidate in identifying different types of cancers. Traditional learning-based cancer identification methods utilize labeled samples to train a classifier, but they
Xiang Zhang, Naiyang Guan, Zhilong Jia, Xiaogang Qiu, Zhigang Luo   +4 more
doaj   +1 more source

Non-negative mixtures

, 2010
This is the author's accepted pre-print of the article, first published as M. D. Plumbley, A. Cichocki and R. Bro. Non-negative mixtures. In P. Comon and C. Jutten (Ed), Handbook of Blind Source Separation: Independent Component Analysis and Applications.
M. D. Plumbley, Bro, Rasmus, Plumbley, MD, Cichocki, A, Cichocki, A., Bro, R, Plumbley, M.D., A. Cichocki, R. Bro, M.D. Plumbley   +9 more
core   +1 more source

Unsupervised learning of overlapping image components using divisive input modulation [PDF]

, 2009
This paper demonstrates that nonnegative matrix factorisation is mathematically related to a class of neural networks that employ negative feedback as a mechanism of competition. This observation inspires a novel learning algorithm which we call Divisive
De Meyer, Kris, Spratling, Michael, Kompass, R., de Meyer, K., Spratling, M.W., Kompass, R   +5 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Short-Text Topic Modeling via Non-negative Matrix Factorization Enriched with Local Word-Context Correlations

The Web Conference, 2018
Being a prevalent form of social communications on the Internet, billions of short texts are generated everyday. Discovering knowledge from them has gained a lot of interest from both industry and academia.
Tian Shi, Kyeongpil Kang, J. Choo, Chandan K. Reddy   +3 more
semanticscholar   +1 more source