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Non-nutritive Sweeteners and Reward Mechanisms
Abstract Over the past several decades, rates of diet-related chronic diseases have risen dramatically, posing a significant public health concern. In an effort to reduce sugar intake and promote weight management, non-nutritive sweeteners are increasingly utilized as a dietary substitute for nutritive sugar consumption, to satiate the ...Kathleen A. Page, Alexandra G. Yunker
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How do non-nutritive sweeteners increase food intake?
Appetite, 1988In short-term tests, rats given saccharin solution to drink eat 10-15% more food than when given only water. This is due to the combination of a cephalic-phase neural reflex that influences liver metabolism, a favorable osmotic environment and learning.
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Natural sweeteners: Sources, extraction and current uses in foods and food industries
Food Chemistry, 2022Roberto Castro-Muñoz +2 more
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The sensory properties and metabolic impact of natural and synthetic sweeteners
Comprehensive Reviews in Food Science and Food Safety, 2021Margaux Mora, Robin Dando
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Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance
Cell, 2022exaly