Gut Microbiome Response to Sucralose and Its Potential Role in Inducing Liver Inflammation in Mice [PDF]
Frontiers in Physiology, 2017 Sucralose is the most widely used artificial sweetener, and its health effects have been highly debated over the years. In particular, previous studies have shown that sucralose consumption can alter the gut microbiota.
Xiaoming Bian, Liang Chi, Bei Gao
exaly +4 more sources
Sucralose and the Gut–Immune Axis: Emerging Evidence Linking Dysbiosis, Barrier Alterations, and Implications for Colitis and Colorectal Cancer Immunotherapy [PDF]
BiomedicinesSucralose is one of the most widely used non-nutritive sweeteners and has long been considered metabolically inert and safe within established acceptable daily intake levels.
Aranza Mejía-Muñoz +4 more
doaj +2 more sources
Sucralose inhibited cell survival through the activation of ER stress in human endothelial progenitor cells. [PDF]
PLoS ONESucralose, a widely utilized non-caloric sweetener, is frequently added to food and beverage products as a sugar substitute aimed at lowering energy consumption and reducing obesity-related health risks.
Chia-Ying Li +4 more
doaj +2 more sources
Sucralose Exposure During Pregnancy Elevates Gestational Diabetes Risk via Gut Microbiota-Metabolic Axis in Mice [PDF]
Journal of Diabetes ResearchSucralose, a widely used nonnutritive artificial sweetener, has gained increasing popularity during pregnancy due to its low-calorie properties. The influence of sucralose on gestational diabetes mellitus (GDM) risk via alterations in gut microbiota ...
Jiajia Song, Juhui He, Zhaoxia Liang
doaj +2 more sources
Re‐evaluation of sucralose (E 955) as a food additive and evaluation of a new application on extension of use of sucralose (E 955) in fine bakery wares [PDF]
EFSA JournalThe present opinion deals with the re‐evaluation of sucralose (E 955) as food additive and with the safety of a proposed extension of use in food category (FC) 7.2 ‘Fine bakery wares’.
EFSA Panel on Food Additives and Flavourings (FAF) +36 more
doaj +2 more sources
Artificial and natural non-nutritive sweeteners drive divergent gut and genetic responses across generations [PDF]
Frontiers in NutritionBackgroundThe role of non-nutritive sweeteners (NNS) in the development of metabolic alterations and chronic non-communicable diseases is controversial.
Francisca Concha Celume +7 more
doaj +2 more sources
Sweeteners in E-Cigarettes: A Minireview of Flavoring and Biological Action [PDF]
Journal of XenobioticsThe use of sweeteners in e-cigarette liquids has become increasingly common, aiming to enhance the sensory appeal of vaping products. Compounds like aspartame, saccharin, and sucralose are added to provide a sweet taste without any calories, especially ...
Volodymyr V. Tkach +6 more
doaj +2 more sources
Effect of Emerging Contaminants (Sucralose) at Relevant Concentrations on Functional Properties in Fish Muscle of Common Carp (Cyprinus carpio) [PDF]
FoodsSucralose, a persistent and widely used artificial sweetener, has emerged as a significant contaminant in aquatic environments, raising concerns about its ecological and physiological effects on aquatic species.
Karinne Saucedo-Vence +10 more
doaj +2 more sources
Effects of sweetener sucralose on diet preference, growth performance and hematological and biochemical parameters of weaned piglets [PDF]
Asian-Australasian Journal of Animal Sciences, 2020 Objective Two experiments were conducted to investigate the effects of dietary sucralose on diet preference and growth performance of weaned piglets, and a third experiment was a 28-d safety study to examine if high-dose sucralose could affect the health
Wenwei Zhang +5 more
doaj +1 more source
Low Doses of Sucralose Alter Fecal Microbiota in High-Fat Diet-Induced Obese Rats
Frontiers in Nutrition, 2021 Artificial sweeteners (AS) have been widely used as sugar substitutes to reduce calorie intake. However, it was reported that high doses of AS induced glucose intolerance via modulating gut microbiota.
Minchun Zhang +9 more
doaj +1 more source