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Azoospermia: a Genomic Review [PDF]
Azoospermia or the absence of sperm in semen is one of the sperm disorders that results in male infertility. There are two types of azoospermia, the first one isazoospermia caused by obstruction of the vas deferens (obstructive azoospermia) and the ...
Larasati, M. D. (Manggiasih) +1 more
core
Objective: To study the prevalence of chromosomal anomalies in infertile males with severe oligozoospermia or non obstructive azospermia and its correlation with clinical and endocrine profile. Patients and methods: Consecutive 30 male subjects (mean age
M.H. Ali +3 more
doaj +1 more source
Background Many circular RNAs (circRNAs) are specifically expressed in the testes and seminal plasma of patients with non-obstructive azoospermia (NOA), highlighting them as potential predictors of microdissection testicular sperm extraction (micro-TESE)
Shengjia Shi +3 more
semanticscholar +1 more source
The use of deidentified organ donor testes for research
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova +4 more
wiley +1 more source
Distribution and number of Cajal-like cells in testis tissue with azoospermia
We investigated the number and distribution of Cajal-like cells in patients with azoospermia. A total of 99 patients with non-obstructive azoospermia were divided into subgroups [19 patientsin hypospermatogenesis group (S1), 40 patients in maturation ...
Eray Hasirci +8 more
doaj +1 more source
Objective The cause and mechanism of non-obstructive azoospermia (NOA) is complicated; therefore, an effective therapy strategy is yet to be developed. This study aimed to analyse the pathogenesis of NOA at the molecular biological level and to identify ...
Qizhen Tang +4 more
semanticscholar +1 more source
Ooplasmic injections of secondary spermatocytes for non-obstructive azoospermia
THE LANCET • Vol 351 • April 18, 1998 1177 difference in frequency of IOL, instrumental vaginal delivery, or Caesarean section between the groups. There was a trend towards a greater number of elective Caesareans among doctors (6/10 of the doctors elective Caesareans were by maternal request compared to 2/7 of the matched controls). Although the number
Sofikitis, N +5 more
openaire +4 more sources
Whole Exome Sequencing Identifies Genes Associated With Non-Obstructive Azoospermia
Background: Non-obstructive azoospermia (NOA) affects nearly 1% of men; however, the landscape of the causative genes is largely unknown. Objective: To explore the genetic etiology which is the fundamental cause of NOA, a prospective ...
Zhang, Hongguo +9 more
openaire +3 more sources
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann +9 more
wiley +1 more source
STAG3 is a strong candidate gene for male infertility [PDF]
Oligo- and azoospermia are severe forms of male infertility. However, known genetic factors account only for a small fraction of the cases. Recently, whole-exome sequencing in a large consanguineous family with inherited premature ovarian failure (POF ...
Barbero, José Luis +8 more
core +3 more sources

