Results 71 to 80 of about 8,317 (213)

Severe male infertility after failed ICSI treatment-a phenomenological study of men's experiences [PDF]

, 2011
Background Male-factor infertility underlies approximately 30% of infertility in couples seeking treatment; of which 10% is due to azoospermia. The development of assisted reproductive technology (ART), enabling the use of epididymal or testicular sperm ...
Marianne Johansson, Anna-Lena Hellström, Marie Berg   +2 more
core   +2 more sources

Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?

Andrology, EarlyView.
ABSTRACT Background Fertility preservation in patients with testicular cancer remains a clinical priority, yet the optimal timing for sperm cryopreservation—before or after orchidectomy—remains a matter of debate. Objectives The aim of this study was to determine the optimal timing for semen cryopreservation and the best‐quality sample for ART.
Alessandra Buonacquisto, Carlotta Pozza, Gaia Cicolani, Anna Chiara Conflitti, Luisa Caponecchia, Serena Bianchini, Enrico Delli Paoli, Marta Tenuta, Daniele Gianfrilli, Andrea M. Isidori, Francesco Lombardo, Francesco Pallotti, Donatella Paoli   +12 more
wiley   +1 more source

The role of varicocele treatment in the management of non-obstructive azoospermia

Clinics, 2013
The literature on male reproductive medicine is continually expanding, especially regarding the diagnosis and treatment of infertility due to non-obstructive azoospermia.
Kubilay Inci, Levent Mert Gunay
doaj  

Can Testicular Size Be a Predictive Factor for Successful Sperm Retrieval in Patients with Non Obstructive Azoospermia?

Gynecology Obstetrics & Reproductive Medicine, 2019
Objective: Non-obstructive azoospermia, defined as absence of spermatozoa in the ejaculate caused by impaired spermatogenesis, is the most severe cause of male infertility.
Omer yumusak, Mehmet Cinar, Serkan Kahyaoglu, Yasemin Tasci, Gul Nihal Buyuk, Aysegul Oksuzoglu   +5 more
doaj   +1 more source

TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse [PDF]

, 2015
Genome‐wide recombination is essential for genome stability, evolution, and speciation. Mouse Tex11, an X‐linked meiosis‐specific gene, promotes meiotic recombination and chromosomal synapsis.
Anderson LK, David C Page, de los Santos T, Fang Yang, Helen Skaletsky, Janet D Marszalek, Laura G Brown, McCarrey JR, N Adrian Leu, P Jeremy Wang, Robert D Oates, Sherman Silber, Steve Rozen   +12 more
core   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Machine learning and integrative analysis identify the common pathogenesis of azoospermia complicated with COVID-19

Frontiers in Immunology, 2023
BackgroundAlthough more recent evidence has indicated COVID-19 is prone to azoospermia, the common molecular mechanism of its occurrence remains to be elucidated.
Jiarong He, Yuanqiao Zhao, Zhixian Zhou, Mingming Zhang   +3 more
doaj   +1 more source

Chromodomain Helicase DNA–Binding Proteins and Spermatogenesis: Current Advances

Andrology, EarlyView.
ABSTRACT Background Male infertility is a prevalent clinical condition, with approximately one‐third of cases classified as idiopathic, frequently stemming from impaired spermatogenesis because of dysregulated gene expression. Chromodomain helicase DNA‐binding (CHD) proteins are central chromatin remodelers that orchestrate this epigenetic regulation ...
Mingrui Zhang, Di Liu, Guoqiang Liu, Minggang Zhu, Feng Pan   +4 more
wiley   +1 more source

Testicular sperm extraction using microdissection for non‐obstructive azoospermia

Reproductive Medicine and Biology, 2002
Background : Men presenting with non‐obstructive azoospermia (NOA) caused by germinal failure can now be treated in some cases using testicular sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI). However, TESE is a blind procedure that does not identify the focal sperm‐producing areas until excision of the ...
Hatsuki, Hibi, Tomohiro, Taki, Yoshiaki, Yamada, Nobuaki, Honda, Hidetoshi, Fukatsu, Masanori, Yamamoto, Yoshimasa, Asada   +6 more
openaire   +2 more sources

Novel mutations of TEX11 are associated with non-obstructive azoospermia

Frontiers in Endocrinology, 2023
Non-obstructive azoospermia (NOA) affects 10% of infertile men worldwide, and genetic studies revealed that there are plenty of monogenic mutations that responsible for a part of idiopathic NOA cases. Testis-expressed gene 11 (TEX11) is an X-linked meiosis-specific gene, many pathogenic variants in TEX11 have been detected in NOA patients, and the ...
Jian Song, Jian Song, Yanwei Sha, Yanwei Sha, Yanwei Sha, Xiaojun Liu, Xuhui Zeng, Xiuling Zhao   +7 more
openaire   +3 more sources