Results 51 to 60 of about 6,194 (199)

Role of testicular fine‐needle aspiration in the modern male reproductive urologist′s practice

UroPrecision, EarlyView.
Abstract Background Azoospermia affects 10%–15% of infertile men, with non‐obstructive azoospermia (NOA) most often managed by microdissection testicular sperm extraction (mTESE). Despite AUA/ASRM guidelines recommending mTESE, some urologists employ testicular fine‐needle aspiration (TFNA) mapping as a diagnostic adjunct.
Parth Joshi, Jordan Kassab, Vivek Aslot, Richard Schoor   +3 more
wiley   +1 more source

Novel mutations of TEX11 are associated with non-obstructive azoospermia

Frontiers in Endocrinology, 2023
Non-obstructive azoospermia (NOA) affects 10% of infertile men worldwide, and genetic studies revealed that there are plenty of monogenic mutations that responsible for a part of idiopathic NOA cases. Testis-expressed gene 11 (TEX11) is an X-linked meiosis-specific gene, many pathogenic variants in TEX11 have been detected in NOA patients, and the ...
Jian Song, Jian Song, Yanwei Sha, Yanwei Sha, Yanwei Sha, Xiaojun Liu, Xuhui Zeng, Xiuling Zhao   +7 more
openaire   +3 more sources

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

Synaptic defects at meiosis I and non-obstructive azoospermia [PDF]

Human Reproduction, 2006
Recent advances in immunofluorescence methodology have made it possible to directly monitor protein localization patterns in germ cells undergoing meiosis. We used this technology to examine the early stages of meiosis in testicular material obtained from men presenting for evaluation at infertility clinics.Specifically, we compared meiotic progression,
TOPPING, Daniel, BROWN, Petrice, JUDIS, Luann, SCHWARTZ, Stuart, SEFTEL, Allen, THOMAS, Anthony, HASSOLD, Terry   +6 more
openaire   +3 more sources

Cellular Therapy via Spermatogonial Stem Cells for Treating Impaired Spermatogenesis, Non-Obstructive Azoospermia [PDF]

, 2021
Male infertility is a major health problem affecting about 8–12% of couples worldwide. Spermatogenesis starts in the early fetus and completes after puberty, passing through different stages.
Jongki Cho, Bereket Molla Tanga, Mai Abdelgawad, Nesma E. Abdelaal, Sahar Allam, Islam M. Saadeldin, Mostafa Fathi, Seonggyu Bang   +7 more
core   +1 more source

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

Andrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann, Johanna Hochmuth‐Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Marta Godlewska, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf   +9 more
wiley   +1 more source

The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia [PDF]

, 2016
Purpose Azoospermia is one of the major causes of male infertility and is basically classified into obstructive (OA) and non-obstructive azoospermia (NOA). The molecular background of NOA still largely remains elusive.
Bassorgun, Ibrahim C., Akkoyunlu, Gokhan, Sozen, Berna, Uysal, Fatma, Usta, Mustafa F., Ozturk, Saffet, Demir, Necdet   +6 more
core   +1 more source

Chromosomal and molecular abnormalities in a group of Brazilian infertile men with severe oligozoospermia or non-obstructive azoospermia attending an infertility service

International Brazilian Journal of Urology, 2011
PURPOSE: To determine the frequency of genetic alterations in a population of Brazilian infertile men with severe oligozoospermia or non-obstructive azoospermia.
Fernanda A. Mafra, Denise M. Christofolini, Bianca Bianco, Marcello M. Gava, Sidney Glina, Sintia I. N. Belangero, Caio P. Barbosa   +6 more
doaj   +1 more source

Analysis of copy number variation in men with non‐obstructive azoospermia

Andrology, 2022
AbstractBackgroundRecent findings demonstrate that single nucleotide variants can cause non‐obstructive azoospermia (NOA). In contrast, copy number variants (CNVs) were only analysed in few studies in infertile men. Some have reported a higher prevalence of CNVs in infertile versus fertile men.ObjectivesThis study aimed to elucidate if CNVs are ...
M. J. Wyrwoll, R. Wabschke, A. Röpke, M. Wöste, C. Ruckert, S. Perrey, N. Rotte, J. Hardy, L. Astica, D. G. Lupiáñez, J. Wistuba, B. Westernströer, S. Schlatt, A. J. Berman, A. M. Müller, S. Kliesch, A. N. Yatsenko, F. Tüttelmann, C. Friedrich   +18 more
openaire   +2 more sources