Results 71 to 80 of about 57,158 (293)

Surgical recovery of sperm in non-obstructive azoospermia [PDF]

Asian Journal of Andrology, 2011
The development of intracytoplasmic sperm injection (ICSI) opened a new era in the field of assisted reproduction and revolutionized the assisted reproductive technology protocols for couples with male factor infertility. Fertilisation and pregnancies can be achieved with spermatozoa recovered not only from the ejaculate but also from the seminiferous ...
openaire   +2 more sources

TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse [PDF]

, 2015
Genome‐wide recombination is essential for genome stability, evolution, and speciation. Mouse Tex11, an X‐linked meiosis‐specific gene, promotes meiotic recombination and chromosomal synapsis.
Anderson LK, David C Page, de los Santos T, Fang Yang, Helen Skaletsky, Janet D Marszalek, Laura G Brown, McCarrey JR, N Adrian Leu, P Jeremy Wang, Robert D Oates, Sherman Silber, Steve Rozen   +12 more
core   +1 more source

An artificial neural network model to diagnose non-obstructive azoospermia based on RNA-binding protein-related genes

Aging, 2023
Non-obstructive azoospermia (NOA) is a severe form of male infertility, but its pathological mechanisms and diagnostic biomarkers remain obscure. Since the dysregulation of RNA-binding proteins (RBPs) had nonnegligible effects on spermatogenesis, we ...
F. Peng, Bahaerguli Muhuitijiang, Jiawei Zhou, Haoyu Liang, Yu Zhang, R. Zhou   +5 more
semanticscholar   +1 more source

Micro RNA in Semen/Urine from Non-Obstructive Azoospermia Patients as Biomarkers to Predict the Presence of Testicular Spermatozoa and Spermatogonia

Life, 2023
About half of testicular sperm extraction (TESE) procedures in men with non-obstructive azoospermia (NOA), including men with Klinefelter syndrome (KS), are unsuccessful. To avoid unnecessary invasive surgery, biomarkers for spermatozoa were studied.
Margo Willems, Céline Devriendt, Catharina Olsen, B. Caljon, T. Janssen, I. Gies, V. Vloeberghs, H. Tournaye, D. Van Saen, E. Goossens   +9 more
semanticscholar   +1 more source

Alterations in the steroid hormone receptor co-chaperone FKBPL are associated with male infertility: a case-control study [PDF]

, 2010
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Barton, David, Campbell, Alan, Cox, Marc B, Crowe, Hannah, De, Leon Johanny M, Downes, CS, Hiripi, Laszlo, Hirst, David, Kaluskar, Soniya, Lagan, Kevin, McDaid, Jennifer R, Miyagawa, Yasushi, Mocanu, Edgar, Robson, Tracy, Scullion, Catherine, Sunnotel, Olaf, Tsujimura, Akira, Walsh, Colum P, Ward, Michael   +18 more
core   +4 more sources

Obstructive and Non-Obstructive Azoospermia

, 2012
Azoospermia is defined as the complete absence of spermatozoa upon examination of the semen [including capillary tube centrifugation (CTC), strictly confirmed by the absence of spermatozoa issued in urine after ejaculation]. The presence of rare spermatozoa (
PASTORE, ANTONIO LUIGI, PALLESCHI, GIOVANNI, SILVESTRI, LUIGI, LETO, ANTONINO, CARBONE, Antonio   +4 more
openaire   +2 more sources

New era of cystic fibrosis: full mutational analysis and personalized therapy [PDF]

, 2017
Despite its apparently simple genetics, cystic fibrosis (CF) is a rather complex genetic disease. A lot of variability in the steps of the path from the cystic fibrosis transmembrane conductance regulator (CFTR ) gene to the clinical manifestations ...
Lucarelli, Marco
core   +1 more source

Correlation of serum FSH and rate of testicular sperm retrieval in non-obstructive azoospermia

Indian Journal of Endocrinology and Metabolism, 2023
Background: Sperm retrieval from men with azoospermia has evolved in recent times, providing patient hope for fulfilling their dream of having their own genetic child through testicular sperm extraction followed by intracytoplasmic sperm injection (TESE ...
Kaberi Banerjee, Bhavana Singla, Kiran Agria   +2 more
doaj   +1 more source

Testosterone to Luteinizing Hormone Ratio as a Potential Predictor of Sperm Retrieval in Non-Obstructive Azoospermia Patients

Yonsei medical journal, 2023
Purpose This study assessed the outcomes of microsurgical testicular sperm extraction (mTESE) and potential preoperative predictors of sperm retrieval (SR) in patients with non-obstructive azoospermia (NOA). Materials and Methods Clinical data of 111 NOA
Tae Jin Kim, K. Koo
semanticscholar   +1 more source

Mapping the Non‐Canonical Splicing Variants: Decrypting the Hidden Genetic Architecture of Idiopathic Male Infertility

Advanced Science, EarlyView.
This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li, Yuge Chen, Dongdong Tang, Yuying Sheng, Xu Han, Hao Geng, Na Zhang, Zongliu Duan, Guanxiong Wang, Yang Gao, Rui Guo, Rong Hua, Zhiming Ding, Chuan Xu, Qunshan Shen, Zhen Yu, Bing Song, Mingrong Lv, Yuping Xu, Huan Wu, Ji Wu, Yunxia Cao, Xiaojin He   +22 more
wiley   +1 more source