Results 81 to 90 of about 54,369 (287)

Whole transcriptome analysis to identify non-coding RNA regulators and hub genes in sperm of non-obstructive azoospermia by microarray, single-cell RNA sequencing, weighted gene co-expression network analysis, and mRNA-miRNA-lncRNA interaction analysis

BMC Genomics
Background The issue of male fertility is becoming increasingly common due to genetic differences inherited over generations. Gene expression and evaluation of non-coding RNA (ncRNA), crucial for sperm development, are significant factors.
Danial Hashemi Karoii, Hossein Azizi, Thomas Skutella   +2 more
semanticscholar   +1 more source

Single-cell multi-omics analysis reveals dysfunctional Wnt signaling of spermatogonia in non-obstructive azoospermia

Frontiers in Endocrinology, 2023
Background Non-obstructive azoospermia (NOA) is the most severe type that leads to 1% of male infertility. Wnt signaling governs normal sperm maturation.
Shengjie Zeng, Liu-xun Chen, Xvdong Liu, Hai Tang, Hao Wu, Chuan Liu   +5 more
semanticscholar   +1 more source

Chromosomal abnormalities in patients with oligozoospermia and non-obstructive azoospermia [PDF]

Journal of Assisted Reproduction and Genetics, 2013
To assess the frequency and types of chromosomal abnormalities in 204 Ukrainian patients with non-obstructive azoospermia and oligozoospermia and 87 men with normozoospermia.Cytogenetic studies were performed on peripheral blood lymphocyte samples of 164 men with oligozoospermia, 40 men with non-obstructive azoospermia and 87 men with normozoospermia ...
Natalia V. Verhoglyad, L. Y. Pylyp, V. Zukin, L. O. Spinenko   +3 more
openaire   +3 more sources

Systematic analysis of protein interaction network associated with azoospermia [PDF]

, 2016
Non-obstructive azoospermia is a severe infertility factor. Currently, the etiology of this condition remains elusive with several possible molecular pathway disruptions identified in the post-meiotic spermatozoa.
Sabetian, S., Shamsir, M. S.
core   +2 more sources

Ooplasmic injections of secondary spermatocytes for non-obstructive azoospermia

The Lancet, 1998
THE LANCET • Vol 351 • April 18, 1998 1177 difference in frequency of IOL, instrumental vaginal delivery, or Caesarean section between the groups. There was a trend towards a greater number of elective Caesareans among doctors (6/10 of the doctors elective Caesareans were by maternal request compared to 2/7 of the matched controls). Although the number
Sofikitis, N., Mantzavinos, T., Loutradis, D., Yamamoto, Y., Tarlatzis, V., Miyagawa, I.   +5 more
openaire   +4 more sources

Biallelic mutations in RNA-binding protein ADAD2 cause spermiogenic failure and non-obstructive azoospermia in humans

Human Reproduction Open, 2023
STUDY QUESTION What are some pathogenic mutations for non-obstructive azoospermia (NOA) and their effects on spermatogenesis? SUMMARY ANSWER Biallelic missense and frameshift mutations in ADAD2 disrupt the differentiation of round spermatids to ...
Baolu Shi, Wasim Shah, Li Liu, Chenjia Gong, Jianteng Zhou, Tanveer Abbas, Hui Ma, Huan Zhang, Menglei Yang, Yuanwei Zhang, Nadeem Ullah, Zubair Mahammad, M. Khan, G. Murtaza, Asim Ali, R. Khan, J. Sha, Yan Yuan, Qinghua Shi   +18 more
semanticscholar   +1 more source

Analysis of copy number variation in men with non‐obstructive azoospermia

Andrology, 2022
AbstractBackgroundRecent findings demonstrate that single nucleotide variants can cause non‐obstructive azoospermia (NOA). In contrast, copy number variants (CNVs) were only analysed in few studies in infertile men. Some have reported a higher prevalence of CNVs in infertile versus fertile men.ObjectivesThis study aimed to elucidate if CNVs are ...
M. J. Wyrwoll, R. Wabschke, A. Röpke, M. Wöste, C. Ruckert, S. Perrey, N. Rotte, J. Hardy, L. Astica, D. G. Lupiáñez, J. Wistuba, B. Westernströer, S. Schlatt, A. J. Berman, A. M. Müller, S. Kliesch, A. N. Yatsenko, F. Tüttelmann, C. Friedrich   +18 more
openaire   +3 more sources

Efficacy of hormone pre‐treatment before ART to improve reproductive outcomes in infertile women with endometriosis: Network meta‐analysis of randomized controlled trials

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Hormone pre‐treatment is still used before assisted reproductive technique (ART) in endometriotic women, but evidence supporting this recommendation is conflicting. Objectives To evaluate whether hormone pre‐treatment with gonadotropin‐releasing hormone (GnRH) agonists or progestogens could improve fertility in women with ...
Gaetano Riemma, Luigi Cobellis, Antonio Simone Laganà, Andrea Etrusco, Luigi Della Corte, Marco Torella, Maria Giovanna Vastarella, Raffaela Maria Carotenuto, Pasquale De Franciscis   +8 more
wiley   +1 more source

Fertility outcome after intracytoplasmic sperm injection with surgically retrieved sperm in obstructive and non-obstructive azoospermia [PDF]

, 2022
Background: Azoospermia is a highly upcoming subject in the last few decades. In the past, use of donor sperm was the only option providing a realistic chance of conception for couples affected by azoospermia.
Devi, Geeta, Gopinathan, K. K., Hooda, Ruchi   +2 more
core   +2 more sources

Pregnancy via Testicular Sperm Extraction for Anejaculation After Neuroblastoma Surgery

IJU Case Reports, EarlyView.
ABSTRACT Background Surgical treatment of a neuroblastoma, a malignant tumor of the sympathetic nervous system, may result in ejaculatory disorder. There are no reports examining ejaculation disorders after neuroblastoma surgery. Case Presentation The patient was a 31‐year‐old Japanese male who had undergone surgery for neuroblastoma of the abdomen at ...
Jurii Karibe, Teppei Takeshima, Daiji Takamoto, Takashi Kawahara, Kimito Osaka, Jun‐ichi Teranishi, Kazuhide Makiyama, Hiroji Uemura, Yasushi Yumura   +8 more
wiley   +1 more source