Results 41 to 50 of about 13,570,701 (304)
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Assessment of three WENO type schemes for nonlinear conservative flux functions [PDF]
INCAS Bulletin, 2018 This paper focuses on a new comparison of the behavior of three Weighted Essentially Non-Oscillatory (WENO) type numerical schemes for three different nonlinear fluxes, in the case of scalar conservation law.
Alina BOGOI +2 more
doaj +1 more source
Condition for Non-Oscillatory Solution for Scalar Convection-Dominated Equation
CFD Letters, 2020 The scalar convection-dominated flows are found in different science and designing applications which incorporates those concerning the computational fluid dynamics problems of mesh structure in the numerical estimations. These flows are thus essential in nature. Despite the fact that these types of flow have been widely discussed among fluid dynamists,
openaire +2 more sources
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
ANTI-DIFFUSION FLUX OPTIMIZATION IN DIFFERENCE SCHEMES FOR ADVECTION EQUATION
Міжнародний науково-технічний журнал "Проблеми керування та інформатики", 2007 Adaptive scheme for numerical solution of the advection equation is considered. The scheme is developed by addition of anti-diffusion terms in the monotone difference scheme of first order.
S.L. Kivva
doaj +1 more source
Results in Applied Mathematics, 2021 This article presents the fifth-order weighted essentially non-oscillatory numerical method for solving a five-equation two-pressure non-conservative model of isentropic two-phase flow.
Asad Rehman +3 more
doaj +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2015 Non-linear viscoelastic behavior of a wormlike micellar solution of cetyltrimethylammonium bromide (CTAB) and sodium salicylate (NaSal) in the large amplitude oscillatory shear (LAOS) is examined. A transient response of the shear stress after applying a
Masatoshi ITO +4 more
doaj +1 more source
Axioms, 2023 This study aims to investigate the asymptotic behavior of a class of third-order delay differential equations. Here, we consider an equation with a middle term and several delays.
Barakah Almarri +3 more
doaj +1 more source