Results 181 to 190 of about 4,733,796 (328)

Non-parametric methods for functional data

, 2020
In this thesis we develop and study non-parametric methods within three major areas of functional data analysis: testing, clustering and prediction. The thesis consists of an introduction to the field, a presentation and discussion of the three areas, and six papers.
openaire   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Variability in the anthelmintic efficacy of levamisole against gastrointestinal nematodes of cattle, sheep and goats in South Darfur, Sudan. [PDF]

BMC Vet Res
Mohammedsalih KM, Ibrahim AIY, Juma FR, Abdalmalaik AAH, Bashar A, von Samson-Himmelstjerna G, Krücken J.   +6 more
europepmc   +1 more source

Non-parametric statistical methods

Advances in Mathematics, 1977
openaire   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Prenatal paracetamol exposure and wheezing in infancy: a targeted maximum likelihood estimation application. [PDF]

BMJ Open Respir Res
Moccia C, Zugna D, Popovic M, Moirano G, Pizzi C, Migliore E, Fariselli P, Sanavia T, Rusconi F, Nybo Andersen AM, Richiardi L, Maule M.   +11 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Deep learning for incidence rate prediction and radiation risk assessment of solid tumors. [PDF]

Sci Rep
Liu Z, Nakamizo T, Misumi M, Ono S, Shuryak I, Ullrich RL.   +5 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Variance reduction with synaptic density imaging in Parkinson's disease using direct-4D PET image reconstruction. [PDF]

Phys Med Biol
Gravel P, Gallezot JD, Fontaine K, Matuskey D, Carson RE.   +4 more
europepmc   +1 more source