Results 81 to 90 of about 4,733,796 (328)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Painful differences between different pain scale assessments: The outcome of assessed pain is a matter of the choices of scale and statistics

Scandinavian Journal of Pain
Perceived pain is a multi-factorial subjective variable, commonly measured by numeric rating scales, verbal descriptive scales (VDS), or by a position on an analogue line (VAS). A major question is whether an individual’s VAS and VDS pain assessments, on
Svensson Elisabeth, Lund Iréne
doaj   +1 more source

A Novel Statistical Test for Life Distribution Analysis: Assessing Exponentiality Against EBUCL Class with Applications in Sustainability and Reliability Data

Axioms
A product’s lifespan may be ascertained by analyzing the dependability and aging class of its life distribution. Sustainability metrics are also crucial for assessing the impact on the environment and creating resource-saving strategies.
Walid B. H. Etman, Mahmoud E. Bakr, Oluwafemi Samson Balogun, Rashad M. EL-Sagheer   +3 more
doaj   +1 more source

Investigating the Impacts of Climate and Land Use Change on the Hydrologic Characteristics in the Sub-Basins of the Dez River, Middle East [PDF]

Water Harvesting Research
Human activities and the climate change affects the river flow therefore monitoring flow rate of river for an extended period can reveal the detail of involved mechanisms in these changes.
Zohreh Khorsandi Kouhanestani
doaj   +1 more source

The Efficiency of German Universities Some Evidence from Non-Parametric and Parametric Methods [PDF]

Due to tight public budget constraints, the efficiency of publicly financed universities in Germany is receiving increasing attention in the academic as well as in the public discourse.
Kempkes, Gerhard, Pohl, Carsten
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A Non-Parametric Approach for the Activation Detection of Block Design fMRI Simulated Data Using Self-Organizing Maps and Support Vector Machine

Journal of Medical Signals and Sensors, 2017
Functional magnetic resonance imaging (fMRI) is a popular method to probe the functional organization of the brain using hemodynamic responses. In this method, volume images of the entire brain are obtained with a very good spatial resolution and low ...
Sheyda Bahrami, Mousa Shamsi
doaj   +1 more source

Non-parametric methods for circular-circular and circular-linear [PDF]

We present a non-parametric approach for the estimation of the bivariate distribution of two circular variables and the modelling of the joint distribution of a circular and a linear variable.
Concepción Ausín, José Antonio Carnicero, Michael P. Wiper   +2 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Investigation of the Soil Depths Temperature Trend Using Parametric and Non-Parametric Methods (Shahrud Station)

علوم آب و خاک, 2019
The effects of climate change can be released from the surface to the soil depth, thereby affecting soil thermal regime. Thermal energy in the soil plays a very important role in causing climate changes. In this study, for the assessment and detection of 
S. Shiukhy Soqanloo, S. Golshan, M. Khoshravesh   +2 more
doaj