Results 41 to 50 of about 195,855 (264)
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna +16 more
wiley +1 more source
Hybrid Fourier series and smoothing spline path non-parametrics estimation model
Pathway analysis is one way to determine whether there is a causal relationship between extrinsic and intrinsic factors. The linearity assumption is something that can change the model. The shape of the model is subject to linearity assumptions.
Atiek Iriany +1 more
doaj +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Optimizing Image Focus for Shape From Focus Through Locally Weighted Non-Parametric Regression
Shape from focus is a passive optical technique that uses multiple images with different focus levels. To compute the sharpness of each pixel in the image sequence, obtained by translating the object plane at a constant step size along the optical axis ...
Hoon-Seok Jang +2 more
doaj +1 more source
This paper investigated the appropriate specifications of Engel curves for non-food expenditure categories and estimated the deprivation indices of non-food needs in rural areas using a semi parametric examination of the presence of saturation points ...
Fuad A Awwad +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Non‐parametric regression under location shifts
Summary: Recent work by \textit{Q. Wang} and \textit{P. C. B. Phillips} [Econometrica 77, No. 6, 1901--1948 (2009; Zbl 1182.62088); Econom. Theory 27, No. 2, 235--259 (2011; Zbl 1210.62126)] has shown that ill-posed inverse problems do not arise in non-stationary nonparametric regression and there is no need for nonparametric instrumental variable ...
PHILLIPS, Peter C. B., SU, Liangjun
openaire +3 more sources
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Abstract Unlike Chap. 6, this chapter focuses on non-parametric transformations of both the response and the explanatory variables. Transformation of the explanatory variables uses the Generalized Additive Model (GAM), described in Sect. 7.2.
Anthony C. Atkinson +4 more
openaire +1 more source

