Results 61 to 70 of about 466,927 (310)

Optimizing Image Focus for Shape From Focus Through Locally Weighted Non-Parametric Regression

IEEE Access, 2019
Shape from focus is a passive optical technique that uses multiple images with different focus levels. To compute the sharpness of each pixel in the image sequence, obtained by translating the object plane at a constant step size along the optical axis ...
Hoon-Seok Jang, Mannan Saeed Muhammad, Tae-Sun Choi   +2 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Smoothing migration intensities with P-TOPALS

Demographic Research, 2020
Background: Age-specific migration intensities often display irregularities that need to be removed by graduation, but two current methods for doing so, parametric model migration schedules and non-parametric kernel regression, have their limitations ...
Sigurd Dyrting
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Complexity-Regularized Regression for Serially-Correlated Residuals with Applications to Stock Market Data

Entropy, 2014
A popular approach in the investigation of the short-term behavior of a non-stationary time series is to assume that the time series decomposes additively into a long-term trend and short-term fluctuations.
David Darmon, Michelle Girvan
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Non-parametric genetic prediction of complex traits with latent Dirichlet process regression models

Nature Communications, 2017
Genetic prediction of complex traits with polygenic architecture has wide application from animal breeding to disease prevention. Here, Zeng and Zhou develop a non-parametric genetic prediction method based on latent Dirichlet Process regression models.
Ping Zeng, Xiang Zhou
doaj   +1 more source

Non Asymptotic Sharp Oracle Inequalities for the Improved Model Selection Procedures for the Adaptive Nonparametric Signal Estimation Problem

Communications, 2018
In this paper, we consider the robust adaptive non parametric estimation problem for the periodic function observed with the Levy noises in continuous time.
Evgeny Pchelintsev, Valeriy Pchelintsev, Serguei Pergamenshchikov   +2 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Un modelo spline para el pronóstico de la demanda de energía eléctrica

Revista Colombiana de Estadística, 2007
El propósito de este trabajo es modelar, con fines de pronóstico, la demanda diaria de energía eléctrica en una región del suroccidente colombiano, mediante la implementación de modelos de regresión no paramétrica teniendo en cuenta factores de ...
ANDRÉS FELIPE BARRIENTOS, JAVIER OLAYA, VÍCTOR MANUEL GONZÁLEZ   +2 more
doaj