Results 51 to 60 of about 466,927 (310)
Hybrid Fourier series and smoothing spline path non-parametrics estimation model
Pathway analysis is one way to determine whether there is a causal relationship between extrinsic and intrinsic factors. The linearity assumption is something that can change the model. The shape of the model is subject to linearity assumptions.
Atiek Iriany +1 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Beta-Stacy survival regression models [PDF]
This paper introduces a class of survival models for discrete time-to-event data with random right censoring. Flexible distributions for the survival times are constructed by modelling the random survival functions as discrete-time beta-Stacy processes (
Muliere, Pietro, Rigat, Fabio
core
A non-parametric investigation of risk premia [PDF]
This paper investigates features of credit risk using non-parametric techniques, studying determinants of risk premia using a non-parametric term-structure model of the corporate spread. The model, which measures the extra return of defaultable corporate
Peroni, Chiara
core +4 more sources
Non‐parametric regression under location shifts
Summary: Recent work by \textit{Q. Wang} and \textit{P. C. B. Phillips} [Econometrica 77, No. 6, 1901--1948 (2009; Zbl 1182.62088); Econom. Theory 27, No. 2, 235--259 (2011; Zbl 1210.62126)] has shown that ill-posed inverse problems do not arise in non-stationary nonparametric regression and there is no need for nonparametric instrumental variable ...
PHILLIPS, Peter C. B., SU, Liangjun
openaire +3 more sources
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Testing Independence of Covariates and Errors in Non‐parametric Regression [PDF]
AbstractConsider a non‐parametric regression modelY=m(X)+ϵ, wheremis an unknown regression function,Yis a real‐valued response variable,Xis a real covariate, andϵis the error term. In this article, we extend the usual tests for homoscedasticity by developing consistent tests for independence betweenXandϵ.
Subhra Sankar Dhar +2 more
openaire +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
This paper investigated the appropriate specifications of Engel curves for non-food expenditure categories and estimated the deprivation indices of non-food needs in rural areas using a semi parametric examination of the presence of saturation points ...
Fuad A Awwad +2 more
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source

