The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication [PDF]
Most RNA viruses infecting mammals and other vertebrates show profound suppression of CpG and UpA dinucleotide frequencies. To investigate this functionally, mutants of the picornavirus, echovirus 7 (E7), were constructed with altered CpG and UpA ...
Atkinson, Nicky J. +3 more
core +2 more sources
Outbreak of Enterovirus D68 in Young Children, Brescia, Italy, August to November 2024
ABSTRACT Enterovirus D68 (EV‐D68) is responsible for a plethora of clinical manifestations ranging from asymptomatic infections to severe respiratory symptoms and neurological disorders. EV‐D68 was first detected in children with pneumonia in 1962 and, from then, only sporadic cases were reported until 2014, when outbreaks were notified across the ...
Serena Messali +9 more
wiley +1 more source
Enteroviruses in Water: Epidemiology, Detection and Inactivation
In this review, enterovirus presence and persistence in water are described. The epidemiology, detection and monitoring and control of enteroviruses are discussed. ABSTRACT Enteroviruses are small non‐enveloped RNA viruses commonly found in environmental water samples.
Corentin Morvan +5 more
wiley +1 more source
Isolation and Public Health Significance of Non-Polio Enteroviruses in Healthy Nigerian Children [PDF]
Non-Polio Enteroviruses (NPEVs) are in circulation all over the world. Some of these viruses have been associated with several chronic diseases such as cardiopathy, myositis, acute flaccid and spastic paralysis in children which mimic poliomyelitis. This study sought to ascertain whether Non-Polio Enteroviruses (NPEVs) are silently shed by apparently ...
Muhammad Sagir Shehu +3 more
openaire +1 more source
Allergen‐Specific Immunotherapy and Trained Immunity
ABSTRACT The high prevalence of allergic diseases reached over the last years is attributed to the complex interplay of genetic factors, lifestyle changes, and environmental exposome. Allergen‐specific immunotherapy (AIT) is the single therapeutic strategy for allergic diseases with the potential capacity to modify the course of the disease.
Leticia Martín‐Cruz, Oscar Palomares
wiley +1 more source
Enteroviruses were investigated in respiratory secretions collected from patients with acute respiratory infections (ARI) over a seven year period (1985-1991), as part of a longitudinal study of ARI aetiology.
Silvana A.R. PORTES +5 more
doaj +1 more source
Vaccination plays a crucial role in mediating protection against infectious diseases, but immune responses to vaccination are highly variable and frequently sub‐optimal in vulnerable populations. Here, we review the latest preclinical and clinical evidence demonstrating that the gut microbiota plays a significant role in regulating immune responses to ...
Charné Rossouw +2 more
wiley +1 more source
Isolation of poliovirus 2C mutants defective in viral RNA synthesis [PDF]
Two poliovirus mutants were isolated that contain an oligonucleotide linker insertion in the 2C-coding region of the viral genome. One, 2C-31, has a strongly temperature-sensitive phenotype and the other, 2C-32, forms small plaques on HeLa cell ...
Baltimore, David, Li, Jing-Po
core
Biological Efficiency of Kunzea ericoides Based On Bioactive Compounds and Impact of Extraction
Exploring the bioactive potential of kānuka (Kunzea ericoides), this review evaluates its antioxidant, antimicrobial, and anti‐inflammatory properties linked to phenolic and terpenoid compounds. The impact of extraction methods on bioactivity highlights kānuka's therapeutic and industrial potential.
Indhuja Devadass +2 more
wiley +1 more source
Sebaran Geografi Non Polio Enterovirus (NPEV) Dari Kasus Layu Akut Di Bagian Barat Indonesia 2007-2010 [PDF]
Acute Flaccid Paralysis (AFP) surveillance which comprises cases and laboratory investigation has been established by WHO in order to achieve the goal of global eradication of polio.
Pangesti, K. N. (Krisna) +2 more
core

