Results 81 to 90 of about 1,607,573 (385)

Implementing a low-threshold audio-only telehealth model for medication-assisted treatment of opioid use disorder at a community-based non-profit organization in Washington, D.C. [PDF]

Harm Reduct J, 2021
Yeo EJ, Kralles H, Sternberg D, McCullough D, Nadanasabesan A, Mayo R, Akselrod H, Catalanotti J.   +7 more
europepmc   +2 more sources

Educational Activities to Help Transferring Knowledge in Nuclear: The Seminars of Spanish Young Generation in Nuclear (Jóvenes Nucleares) [PDF]

, 2011
From its creation, Spanish Young Generation in Nuclear (Jóvenes Nucleares, JJNN), a non-profit organization that depends on the Spanish Nuclear Society (SNE), has as an important scope to help transferring the knowledge between those generations in the ...
Alvarez, A., Jiménez Varas, Gonzalo, Ortega, S., Rubio, Rafael, Sánchez, M.   +4 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Innovation practices in a non-profit portuguese organization [PDF]

, 2014
This article is a case study of a Social Economic Organization, where we will examine, in the light of the literature on strategic management, and innovation, its organizational change, which was critical to ensure its survival. Through this case study
Barbosa, Fernando de Oliveira, Romero, Fernando   +1 more
core  

Crowdfunding Astronomy Research with Google Sky [PDF]

, 2015
For nearly four years, NASA's Kepler space telescope searched for planets like Earth around more than 150,000 stars similar to the Sun. In 2008 with in-kind support from several technology companies, our non-profit organization established the Pale Blue ...
Metcalfe, Travis S.
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diabetes: It\u27s more than a little sugar [PDF]

, 2010
Thomas Jefferson University Hospital – Office to Advance Population Health Sponsored by Quality Insights of Pennsylvania: Under contract with the Centers for Medicare and Medicaid Services (CMS), protects Medicare patient rights and works collaboratively

core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Rational therapy of acute viral rhinosinusitis in outpatient practice

Лечащий Врач
Background. Acute respiratory viral infections are the most common reason for seeking care from outpatient physicians. Most cases of acute respiratory viral infections are caused by different serotypes of respiratory viruses, which cause diseases with ...
A. A. Stremoukhov
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source