Results 131 to 140 of about 12,220,401 (374)

Em nome da autonomia e do desenvolvimento

Meridiano 47, 2017
The objective is to examine the positions adopted by Brazil on nuclear non-proliferation, disarmament and peaceful uses of nuclear energy in the beginning of this century.
Diego Santos Vieira de Jesus
doaj  

Long non‐coding RNA OIP5‐AS1 promotes proliferation of lung cancer cells and leads to poor prognosis by targeting miR‐378a‐3p [PDF]

, 2018
Maolong Wang, Xiao Sun, Yuling Yang, Wenjie Jiao   +3 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Comments on Fouchier's Calculation of Risk and Elapsed Time for Escape of a Laboratory-Acquired Infection from His Laboratory

mBio, 2015
Lynn C. Klotz
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Knockdown of MRPL35 promotes cell apoptosis and inhibits cell proliferation in non-small-cell lung cancer [PDF]

, 2023
Chengling Zhao, Lei Chen, Zhixin Jin, Haitao Liu, Chao Ma, Hangtian Zhou, Lingling Xu, Sihui Zhou, Yan Shi, Wei Li, Yuqing Chen, Chengli Dou, Xiaojing Wang   +12 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Russia´s Non-Proliferation Policy and the Challenges of Rogue Proliferation

Revista UNISCI, 2012
Este artículo analiza el papel de Rusia en los esfuerzos globales de no-proliferación, ofreciendo una visión global sobre la no proliferación rusa, desarme y políticas de control de armamentos.
Natividad Fernández
doaj  

Cell Proliferation and DNA Synthesis in Organizing White Mural Non-Occlusive Aortic Thrombus in Rabbits [PDF]

, 1977
Jacob Rabinovitch, Bernard I. Weigensberg, Robert H. More, A I Gotlieb   +3 more
openalex   +1 more source

CircKIF4A promotes non-small cell lung cancer proliferation and metastasis through MiR-1238/CLDN14 axis [PDF]

, 2022
Weimin Luo, Yuefeng Liu, Hangying Qu, Xiangyu Luo, Liqiang Xu, Jia Zhang, Jiansheng Wang   +6 more
openalex   +1 more source