Results 201 to 210 of about 12,220,401 (374)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance. [PDF]

Oncol Lett
Zhang C, Ma J, Wang W, Guo M, Han C, Sadike M, Zhu K.   +6 more
europepmc   +1 more source

Retraction: Down-regulation of lncRNA XIST inhibits cell proliferation via regulating miR-744/RING1 axis in non-small cell lung cancer [PDF]

openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

The role of impaired adipogenesis in insulin resistance among non-obese individuals. [PDF]

Front Physiol
Almuraikhy S, Alser M, Naja K, Anwardeen N, Taha S, John J, Halim S, Badran S, Ahmed MB, Jarrar S, Aljassem G, Al-Mohannadi FS, Doi S, Abdel-Aziz A, Elaf YJ, Elrayess MA.   +15 more
europepmc   +1 more source

Long non-coding RNA UCA1a(CUDR) promotes proliferation and tumorigenesis of bladder cancer

, 2012
Yu Wang
openalex   +2 more sources

Silencing of long non-coding RNA PCAT6 restrains gastric cancer cell proliferation and epithelial-mesenchymal transition by targeting microRNA-15a

, 2020
Dongfang Dong, Yue Lun, Bo Sun, Haiyuan Sun, Qunying Wang, Gang Yuan, Jingzi Quan   +6 more
openalex   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Continuous-time random walk diffusion MRI facilitates assessment of Ki-67 expression in endometrial cancer: a comparative study with diffusion kurtosis imaging. [PDF]

BMC Cancer
Liu W, Ren J, Li Z, Liu W, Wang S, Ba Y, Jiang B, Han D, Yan R.   +8 more
europepmc   +1 more source

Decreased expression of long non-coding RNA SNHG7 cause recurrent spontaneous abortion through suppression proliferation and invasion of trophoblast cells via miR-34a.

, 2019
Haiyun Xiang, Hua Yan, Bingmei Sun, Fu‐Zhong Feng, Ping Chen   +4 more
openalex   +1 more source