Results 201 to 210 of about 1,391,444 (333)

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

16P Long intergenic non-coding RNA 00152 promotes lung adenocarcinoma proliferation via interacting with EZH2 and repressing IL24 expression [PDF]

, 2018
C. Qinnan, Zhaoxia Wang
openalex   +1 more source

Challenges to the International Nuclear Non-Proliferation Regime [PDF]

, 2003
Kurosawa, Mitsuru
core  

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Calcitonin receptor downregulation and exercise-conditioned blood enable systemic muscle stem cell proliferation. [PDF]

Nat Commun
Zhang L, Kaji T, Nakamura A, Maesawa N, Iwamori K, Xu J, Liu Y, Uezumi A, Kamimura D, Murakami M, Kubo A, Yamada T, Akimoto T, Fukada SI.   +13 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review). [PDF]

Oncol Rep
Wang K, Li Y, Guo Z, Song L, Ding X, Liu L, Hu T, Bian Y, Huang C, Miao L.   +9 more
europepmc   +1 more source

Russia’s Non-Proliferation Policy and the Challenges of Rogue Proliferation

, 2014
Natividad Fernández Sola
openalex   +2 more sources

Quercetin Inhibits the Proliferation and Metastasis of Human Non-Small Cell Lung Cancer Cell Line: The Key Role of Src-Mediated Fibroblast Growth Factor-Inducible 14 (Fn14)/ Nuclear Factor kappa B (NF-κB) pathway

, 2020
Yan Dong, H. J. Yang, Liyuan Yang, Ping Li   +3 more
openalex   +2 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source