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The Hazard of Non-proportional Hazards in Time to Event Analysis

European Journal of Vascular and Endovascular Surgery, 2021
Lorenz Meuli, Christoph Kuemmerli
openaire   +4 more sources

On a non‐proportional hazards regression model for repeated medical random counts

Statistics in Medicine, 1997
A wholly parametric non-proportional hazards survival model is introduced. The model retains Cox's constant of proportionality as the leading term in the relative risk but permits additional flexibility by modelling the relative risk as a function of time.
openaire   +3 more sources

Estimation of Main Effect When Covariates Have Non-Proportional Hazards

Communications in Statistics - Simulation and Computation, 2014
The Cox proportional hazards (PH) regression model has been widely used to analyze survival data in clinical trials and observational studies. In addition to estimating the main treatment or exposure group effect, it is common to adjust for additional covariates using the Cox model.
Ronghui Xu, Xinyi Lin, Erika Strandberg
openaire   +2 more sources

Analysis of Multivariate Survival Times with Non-Proportional Hazards Models

1997
In a clinical trial to evaluate treatments for a chronic disease, a commonly used regression method for analyzing multiple event times is based on a multivariate Cox model (Wei, Lin and Weissfeld, 1989). However, the Cox model may not fit the data well.
L. Chen, L. J. Wei
openaire   +2 more sources

Latent heterogeneity effects in modelling individual hazards: A non-proportional approach

Technological Forecasting and Social Change, 2016
Abstract This paper proposes an extension of individual hazard modelling through diffusion of innovation methodologies with the introduction of latent neighbouring effects in individual hazards. The proposal combines the Bemmaor's methodology for latent heterogeneous factors in the Cox proportional hazards model.
openaire   +2 more sources

Dealing with non-proportional hazards [PDF]

open access: possible, 2011
Hans C. van Houwelingen, Hein Putter
openaire   +1 more source

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