Results 71 to 80 of about 11,030,662 (278)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
On fracture loci of ductile materials under non-proportional loading [PDF]
International Journal of Mechanical Sciences, 2016 Abstract For general stress states the fracture locus, under strictly proportional loadings, may be viewed as a two dimensional surface. Deviations from that locus under non-proportional loadings have received limited attention in the literature. The general problem is quite complex because of unavoidably intertwined history effects on both damage ...
Nithin Thomas +2 more
openaire +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The proportional representation review.
, 1893 Continued as a department of: Direct legislation record and the proportional representation review."A quarterly magazine, devoted to the reformation of the method of electing representatives."Title from cover.Mode of access: Internet.Revived and absorbed
American Proportional Representation League.
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Proportional representation review
, 1914 Includes supplements.Includes supplements.Mode of access: Internet.Organ of the Proportional Representation League (called, 1914-1920, American Proportional Representation League).The Proportional representation review (v. 1-3) was issued in Chicago from
American Proportional Representation League. +1 more
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The paper addresses the numerical calculation of multi-axial fatigue crack propagation in ductile materials under proportional and non-proportional cyclic loading conditions. The analysis is based on a phase field fracture theory proposed in earlier work,
Tsakmakis, Aris +2 more
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Journal of Materials Research and Technology, 2015 A critical issue in multiaxial damage calculation in non-proportional (NP) histories is to find the equivalent stress or strain ranges and mean components associated with each rainflow-counted cycle of the stress (or strain) path.
Marco Antonio Meggiolaro +1 more
doaj +1 more source