Results 61 to 70 of about 11,030,662 (278)
Testing for Proportional Hazards with Unrestricted Univariate Unobserved Heterogeneity [PDF]
, 2009 We develop tests of the proportional hazards assumption, with respect to a continuous covariate, in the presence of unobserved heterogeneity with unknown distribution at the individual observation level.
Bhattacharjee, Arnab +1 more
core
Nihon Kikai Gakkai ronbunshu, 2020 In a pressure vessel, a heat exchanger and a junction piping where cold and hot water are mixed, temperature fluctuation yields multiaxial stress and random amplitude loading conditions.
Takahiro MORISHITA +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fatigue strength of welded joints under multiaxial non-proportional loading
Procedia Structural Integrity, 2017 Abstract Fatigue behaviour of a fillet-welded tubular T-joint in the so-called H structural component of an agricultural sprayer is examined by using experimental strain measurements found in the literature and linear elastic finite element analyses.
Sabrina Vantadori +8 more
openaire +3 more sources
Biaxial Testing of Thin Metal Sheets under Non-Proportional Loading Conditions
MetalsDuring the manufacturing and service of thin metal sheets, different stress states occur, often caused by non-proportional loading conditions. They can lead to localization of inelastic deformations as well as to damage and failure processes.
Steffen Gerke +2 more
doaj +1 more source
Cyclic Deformation and Low-Cycle Fatigue for 316LN Stainless Steel under Non-proportional Loading [PDF]
MATEC Web of Conferences, 2019 The effects of loading path and strain amplitude ratio on the cyclic behavior and fatigue life were investigated on a 316LN nuclear grade stainless steel employing a series of symmetrically strain-controlled fatigue tests at room temperature. The loading
Li Yajing, Ren Bin, Chen Xu
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Taking into account the non-proportional loading effect on high cycle fatigue life predictions obtained by invariant-based approaches [PDF]
MATEC Web of Conferences, 2019 Industrial structures are often subjected to multiaxial fatigue loadings. If the multiple stress signals are not synced the loading is said to be non-proportional.
Bercelli Lorenzo +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Evaluation and visualization of multiaxial fatigue behavior under random non-proportional loading condition [PDF]
Fracture and Structural Integrity, 2017 In cyclic multiaxial stress/strain condition under nonproportional loading in which principal direction of stress/strain are changed in a cycle, it becomes difficult to analyze stress/strain ranges because of complexity of multiaxial stress/strain states
Takahiro Morishita +2 more
doaj +1 more source