Results 41 to 50 of about 147,595 (279)

Fatigue Life Assessment of Metals under Multiaxial Asynchronous Loading by Means of the Refined Equivalent Deformation Criterion

open access: yesMetals, 2023
As is well-known, non-proportional fatigue loading, such as asynchronous one, can have significant detrimental effects on the fatigue behavior of metallic materials by reducing the fatigue strength/fatigue limit and by leading to a fatigue damage ...
Daniela Scorza
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Multiaxial Low Cycle Fatigue Life of Sn-8Zn-3Bi Solder under Non-proportional Loading

open access: yes, 2017
This study describes evaluation of multiaxial low cycle fatigue life of a lead-free solder, Sn-8Zn-3Bi. Strain controlled multiaxial low cycle fatigue tests under proportional and non-proportional loading conditions were carried out using a hollow ...
Itoh, Takamoto   +5 more
core   +1 more source

Non-local energy based fatigue life calculation method under multiaxial variable amplitude loadings [PDF]

open access: yes, 2013
Reliable design of industrial components against high cycle multiaxial fatigue requires a model capable of predicting both stress gradient and load type effects. Indeed, taking into account gradient effects is of prior importance for the applicability of
PALIN-LUC, Thierry   +4 more
core   +1 more source

Tube Expansion by Single Point Incremental Forming: An Experimental and Numerical Investigation

open access: yesMetals, 2021
In this paper, we revisit the formability of tube expansion by single point incremental forming to account for the material strain hardening and the non-proportional loading paths that were not taken into consideration in a previously published ...
Carlos Suntaxi   +4 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Low-Cycle Fatigue of Aa2124t851 [PDF]

open access: yesTransactions of the VŠB-Technical University of Ostrava, Mechanical Series, 2016
This paper presents an overview of extensive set fatigue tests results in low-cycle domain carried out at the Department of Applied Mechanics at the VŠB – Technical University of Ostrava on smooth specimens made of 2124T851 aluminum alloy.
Radim Halama   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Evaluating shakedown under proportional loading by non-linear static analysis

open access: yes, 2003
A lower bound method for calculating shakedown loads under proportional loading by static non-linear finite element analysis is presented. Stress fields obtained by static analysis and stress superposition are substituted into Melan's lower bound ...
Muscat, Martin   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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