Results 41 to 50 of about 7,040,883 (266)

Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex   +13 more
wiley   +1 more source

The epistemology of testimony: reductionism vs antireductionism. [PDF]

open access: yes, 2016
This dissertation discusses one of the most fundamental issues of the epistemology of testimony, that is, how the hearer ascribes trustworthiness to the speaker’s testimony.
MONDAL, GOPI NATH
core   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko   +19 more
wiley   +1 more source

Competencias directivas requeridas por los CEO ante la complejidad de las organizaciones del siglo xxi

open access: yesSuma de Negocios, 2016
This article aims to present complexity as an intangible, non-linear, large, and unstable reality of the environment, and theoretically explained by their axes. It shows the evolution of the organisation from its beginning to the new organisational forms,
Monica Flores Marin , Guiseppe Vanoni
doaj   +1 more source

T2* Magnetic Resonance Imaging Uncovers Hemosiderin Burden in Pediatric Hemophilia: A Call for Sensitive Imaging Biomarkers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hemophilic arthropathy remains the leading morbidity in hemophilia despite modern prophylaxis, and early joint damage may be missed by routine exams. This study explored T2* MRI as a noninvasive biomarker of hemosiderin deposition in pediatric hemophilia.
Jessica Garcia   +6 more
wiley   +1 more source

Theory reduction by means of functional sub-types [PDF]

open access: yes, 2007
The paper sets out a new strategy for theory reduction by means of functional sub-types. This strategy is intended to get around the multiple realization objection.
Christian Sachse   +3 more
core  

Global Health – emergence, hegemonic trends and biomedical reductionism

open access: yesGlobalization and Health, 2020
Background Global Health has increasingly gained international visibility and prominence. First and foremost, the spread of cross-border infectious disease arouses a great deal of media and public interest, just as it drives research priorities of ...
Jens Holst
doaj   +1 more source

Survival by Race and Ethnicity in Children and Adolescents/Young Adults With Relapsed/Refractory Hodgkin Lymphoma: A Pooled Analysis of Children's Oncology Group Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Despite 5‐year survival rates of over 90% among children and adolescents/young adults (CAYAs) with classic Hodgkin lymphoma (cHL), 15%–20% relapse after frontline therapy. Prior analysis of frontline Children's Oncology Group (COG) clinical trials demonstrated that, despite similar rates of relapse, non‐Hispanic Black (NHB) and ...
Mallorie B. Heneghan   +14 more
wiley   +1 more source

Beyond Theoretical Reduction and Layer-Cake Antireduction: How DNA Retooled Genetics and Transformed Biological Practice [PDF]

open access: yes, 2008
Watson and Crick’s discovery of the structure of DNA led to developments that transformed many biological sciences. But what were the relevant developments and how did they transform biology?
Waters, C. Kenneth
core  

Rupture et continuité dans la physique française : Henri Poincaré et les fondements mécaniques de la thermodynamique

open access: yesPhilosophia Scientiæ, 2023
After 1850, Laplacian or Amperean molecular physics found itself in competition with other approaches involving thermodynamics and kinetic theories. Henri Poincaré is one of the very few French scientists to have made a significant contribution to the ...
João Príncipe
doaj   +1 more source

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