Results 131 to 140 of about 14,903,668 (313)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
MathematicsThere is a difficulty in survey sampling when non-response (NR) occurs in the process of estimating the population parameters. This study examines the effectiveness of combined and separate log-type estimators when using bivariate auxiliary information ...
G. R. V. Triveni +2 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
2016 NRPT: Addressing Public Concerns During Spill Response
, 2016 On June 28-29, 2016, the Coastal Response Research Center (CRRC) and the National Oceanic and Atmospheric Administration (NOAA) Gulf of Mexico Disaster Response Center (DRC) co-sponsored a NOAA Regional Preparedness Training (NRPT) workshop at the ...
Coastal Response Research Center (CRRC)
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A study of response and non-response to postal questionnaire follow-up in clinical trials [PDF]
Postal questionnaires offer one of the least expensive modes of collecting patient based outcomes in health care research. Many methods of increasing response to questionnaires used in educational and market research surveys have been tested. Behavioural
Nakash, Rachel Anne
core
Effect of tufting on the response of non crimp fabric composites. [PDF]
, 2007 This paper examines the effectiveness of tufting in enhancing the through the thickness properties of non crimped fabrics. The response of tufted and untufted carbon/epoxyn on crimped fabric composites produced using resin infusion is investigated in ...
Witzel, Volker +3 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source