Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Development and validation of machine learning models for predicting rehabilitation non-response after knee arthroplasty. [PDF]
Hubel NJ +6 more
europepmc +1 more source
Missing data in FFQs: making assumptions about item non-response
OBJECTIVE: FFQs are a popular method of capturing dietary information in epidemiological studies and may be used to derive dietary exposures such as nutrient intake or overall dietary patterns and diet quality.
KE Lamb (9898403) +4 more
core
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Predictors for non-response to PROMs across three areas of inpatient rehabilitation - a nationwide cross-sectional study in Switzerland. [PDF]
Basedow F +9 more
europepmc +1 more source
Non-response and attrition in longitudinal studies
openaire +3 more sources
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Non-response biases in surveys of school children: the case of the English PISA samples [PDF]
We analyse response patterns to an important survey of school children, exploiting rich auxiliary information on respondents’ and non-respondents’ cognitive ability that is correlated both with response and the learning achievement that the survey aims ...
Chris Skinner +2 more
core
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Evaluating evidence based options for initial PTSD treatment non-response: A randomized controlled trial protocol. [PDF]
Held P +8 more
europepmc +1 more source

