Results 171 to 180 of about 710,958 (307)

N1‐methylpseudouridine modification level correlates with protein expression, immunogenicity, and stability of mRNA

MedComm
Shaoyi Chen, Zheng Liu, Jingsheng Cai, Haoran Li, Mantang Qiu   +4 more
doaj   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source

Tumor immune microenvironment in non-small cell lung cancer progression. [PDF]

Front Immunol
Jiang J, Zhong M, Wang J, Zhang Z, Li W, Deng Z.   +5 more
europepmc   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

Brigatinib for ALK-positive metastatic non-small-cell lung cancer: design, development and place in therapy

, 2019
Robert Ali,1 Junaid Arshad,1 Sofia Palacio,1 Raja Mudad2 1Department of Medicine, Division of Oncology, Jackson Memorial Hospital, University of Miami, Miller School of Medicine, Sylvester Comprehensive Cancer Centre, Miami, FL 33131, USA; 2Department ...
Arshad J, Mudad R, Ali R, Palacio S
core  

The Role of Immunotherapy in Resectable Non-Small Cell Lung Cancer. [PDF]

Oncol Res
Petrella F, Cara A, Cassina EM, Libretti L, Pirondini E, Raveglia F, Sibilia MC, Tuoro A.   +7 more
europepmc   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

HER2-Mutant Non-Small Cell Lung Cancer Podcast: Knowledge Is Power. [PDF]

Target Oncol
Subbiah V, Dietrich M, Le X.
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer. [PDF]

Oncol Rep
Zhou Y, Li R, Chen X, Zhang C, Bao Y, Cui Y, Tong X, Xia T, Yang X, Yang J, Yin X.   +10 more
europepmc   +1 more source